The Effect of Histamine Antagonists on Gastric Secretion

Abstract

The APS Journal Legacy Content is the corpus of 100 years of historical scientific research from the American Physiological Society research journals. This package goes back to the first issue of each of the APS journals including the American Journal of Physiology, first published in 1898. The full text scanned images of the printed pages are easily searchable. Downloads quickly in PDF format.

Metabolite Antagonists.

“…Numerous investigations have verified the antihistamine activity of I and II (71,353,354,434), but there appears to be no general agreement as to the specificity of these antagonists. Both compounds have been reported to be in- effective or non-specific in reducing the gastric secretion in dogs following histamine stimulation (44,53,154,238).…”