The effect of growth factors for bone augmentation to enable dental implant placement: A systematic review

Tsantis

et al. 2014

ccmbm

Section: Introductionmentioning

confidence: 99%

The impact of Platelet Rich Plasma (PRP) in osseointegration of oral implants in dental panoramic radiography: texture based evaluation

Tsantis

et al. 2014

ccmbm

“…Implant therapy is known as the best method for the restoration of edentulous sites [1]. Prosthetic implantation requires the presence of sufficient high-quality bone.…”

Section: Introductionmentioning

confidence: 99%

Periosteal Envelope Flap as a Technique for Horizontal Bone Augmentation: A Case Series Study

Arab¹,

Arab²,

Aghaloo³

et al. 2018

TODENTJ

Background:Following tooth extraction, the alveolar bone is typically subject to irrevocable and progressive changes that are collectively referred to as natural bone resorption. This process eventually results in a deficiency of the vertical and horizontal dimensions of the bone. Conventionally, various methods are used to repair alveolar defects resulting from tooth extraction, and to achieve vertical or horizontal bone regeneration. The aim of this study was to evaluate the influence of periosteal pocket flap on the enhancement of horizontal length in alveolar bone regeneration. Methods:Twenty-two patients (7 men, 15 women) aged 45-60 years were enrolled in this study. Periosteal envelope flaps and Cerabone were used to increase alveolar bone thickness. Ridge width was measured preoperatively and 4-6 months postoperatively using cone-beam computed tomography. The pre-and postoperative results were compared using the paired t-test. Results:An average of 2.53 mm (P < 0.001) horizontal enhancement of the alveolar ridge was achieved. Conclusion:The results of this study suggest that the use of a periosteal pocket flap with xenograft material is an excellent method which increase more than 2 mm alveolar bone width. As the study sample was small, further clinical investigations with larger samples are recommended.

J. Hard Tissue Biology.

“…The clinical applications of hard tissue regeneration therapy have been reported for autogenous or artificial bone grafts in dental practice 2) , guided tissue regeneration 3) , and growth factors 4,5) .…”

Section: Introductionmentioning

confidence: 99%

Changes of Vascular Endothelial Growth Factor and Platelet-derived Growth Factor Concentrations in Platelet-rich Plasma After Preparation

Suwa

Nakanishi

Kato-Kogoe

et al. 2017

Platelet-rich plasma (PRP) is plasma that contains platelets concentrated by centrifugal separation of a blood specimen. Advances in the practical applications of PRP have enabled regenerative therapies for hard tissue. Blood contains many growth factors. Therefore, to more effectively use PRP in the clinical setting, it is important to evaluate how growth factor levels change after PRP preparation. The objective of the present study was to observe how the concentrations of vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) in PRP change after preparation. PRPs were prepared from 17 healthy consenting male and female subjects aged 25-32 years. Enzyme-linked immunosorbent assay (ELISA) was used to measure the VEGF and PDGF concentrations at 15, 30, 60, 120 and 1,440 min after PRP preparation. We found that VEGF and PDGF concentrations remained high, and exhibited their highest levels at 24 h after PRP production. This persistence suggests that VEGF and PDGF might remain active in tissue regeneration, even 24 h after PRP is prepared.