The Effect of Green Tea and Sour Tea on Blood Pressure of Patients with Type 2 Diabetes: A Randomized Clinical Trial

Mozaffari‐Khosravi, Hassan; Ahadi, Zeinab; Barzegar, Kazem

doi:10.3109/19390211.2013.790333

Cited by 69 publications

(91 citation statements)

References 43 publications

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“…The Wistar rats were used to perform the renal ischemia/reperfusion surgery, as described previously (24,25). Briefly, the rats were anesthetized by intraperitoneal (i.p.)…”

Section: Methodsmentioning

confidence: 99%

Honokiol protects against renal ischemia/reperfusion injury via the suppression of oxidative stress, iNOS, inflammation and STAT3 in rats

et al. 2015

Molecular Medicine Reports

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Abstract. Honokiol is the predominant active ingredient in the commonly used traditional Chinese medicine, Magnolia, which has been confirmed in previous studies to exhibit anti-oxidation, antimicrobial, antitumor and other pharmacological effects. However, its effects on renal ischemia/reperfusion injury (IRI) remain to be elucidated. The present study aimed to examine the effects of honokiol on renal IRI, and to investigate its potential protective mechanisms in the heart. Male adult Wistar albino rats were induced into a renal IRI model. Subsequently, the levels of serum creatinine, blood urea nitrogen (BUN), alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP), and the levels of serum nitrite and the kidney nitrite were examined in the IRI group. The levels of oxidative stress, inducible nitric oxide synthase (iNOS), inflammatory factors and caspase-3 were evaluated using a series of commercially available kits. The levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3) and the protein expression levels of STAT3 were determined using western blotting. Pretreatment with honokiol significantly reduced the levels of serum creatinine, BUN, ALT, AST and ALP, and the level of nitrite in the kidney of the IRI group, compared with the control group. The levels of malondialdehyde, the activity of myeloperoxidase, and the gene expression and activity of iNOS were reduced in the IRI rats, compared with the sham-operated rats, whereas the levels of superoxide dismutase and catalase were increased following treatment with honokiol in the IRI rats. In addition, the expression levels of tumor necrosis factor-α and interleukin-6 in the IRI rats were increased by honokiol. Treatment with honokiol suppressed the protein expression levels of p-STAT3 and caspase-3 in the IRI rats. These findings indicated that honokiol protects against renal IRI via the suppression of oxidative stress, iNOS, inflammation and STAT3 in the rat.

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“…The Wistar rats were used to perform the renal ischemia/reperfusion surgery, as described previously (24,25). Briefly, the rats were anesthetized by intraperitoneal (i.p.)…”

Section: Methodsmentioning

confidence: 99%

Honokiol protects against renal ischemia/reperfusion injury via the suppression of oxidative stress, iNOS, inflammation and STAT3 in rats

et al. 2015

Molecular Medicine Reports

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“…It was shown following an evaluation of factors such as blood glucose, insulin, lipid profile, and antioxidant levels, that both plants were effective in reducing antioxidant levels and the lipid profile (19).…”

Section: The Role Of Antioxidantsmentioning

confidence: 99%

Effect and Mechanism of Herbal Ingredients in Improving Diabetes Mellitus Complications

Ebrahimi

Shirali

Afrisham

2016

Jundishapur J Nat Pharm Prod

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Context: Diabetes mellitus is the most common endocrine disease worldwide and its prevalence is increasing. The development of drugs with fewer side-effects is required when treating this disease. Thus, the objective of this study was to evaluate the use of traditional medicine and medicinal plants in this regard. The various mechanisms by which isolated extracts and herbal compounds exert their effects on different diabetes mellitus factors was investigated. Evidence Acquisition: Databases such as PubMed, Science Direct, and Web of Science (from 1990 until the present) were searched, using a detailed list of terms related to the effects and mechanism of herbal ingredients on diabetes mellitus complications. Results:The presence of secondary metabolites, such as phenols, flavonoids and alkaloids in plants, have been used as a source of medication for the treatment of many diseases, including diabetes mellitus. Following an extensive review of the literature, it was found that the secondary metabolites of plants have a wide range of anti-diabetic effects. Conclusions: Plant compounds should be isolated and their effects on diabetes mellitus and its complications examined in order to treatment for diabetes mellitus.

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“…In addition, the effect of individual foods on BP has been investigated in randomized controlled trials and observational studies but with conflicting results. Foods investigated include fruit and vegetables [9], dairy foods [10], eggs [11], nuts [12], pulses [13], meat [14], tea [15] and coffee [16].…”

Section: Introductionmentioning

confidence: 99%

Associations between Dietary Patterns and Blood Pressure in a Clinical Sample of Overweight Adults

Ndanuko¹,

Tapsell²,

Charlton³

et al. 2017

Journal of the Academy of Nutrition and Dietetics

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The Effect of Green Tea and Sour Tea on Blood Pressure of Patients with Type 2 Diabetes: A Randomized Clinical Trial

Abstract: The present study revealed that mildly hypertensive type 2 diabetic individuals who drink three glasses of green or sour tea daily for 4 weeks show significant decreased systolic and diastolic blood pressures.

Cited by 69 publications

References 43 publications

Honokiol protects against renal ischemia/reperfusion injury via the suppression of oxidative stress, iNOS, inflammation and STAT3 in rats

Honokiol protects against renal ischemia/reperfusion injury via the suppression of oxidative stress, iNOS, inflammation and STAT3 in rats

Effect and Mechanism of Herbal Ingredients in Improving Diabetes Mellitus Complications

Associations between Dietary Patterns and Blood Pressure in a Clinical Sample of Overweight Adults

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