The effect of gradual distraction of the mandible on the sheep temporomandibular joint

The effect of irradiation and hyperbaric oxygenation (HBO) on extracellular matrix of the condylar cartilage after mandibular distraction osteogenesis in the rabbit

“…Nevertheless, the substantial loss of PGs and replacement of type II with type I collagen leads inevitably to a considerable loss of cartilage function on the operated side in the irradiated groups, indicating that previous radiotherapy is a high risk of degenerative changes if DO treatment is applied. It should be pointed out that despite considerable lengthening of the mandible, the used distraction frequency and the age of the animals the condylar cartilages of the distracted control rabbits did not reveal major adverse effects, which is in accordance with previous studies 4,8 .…”

“…The morphology of a deformed TMJ may even be improved as a result of DO treatment 8,15 . After unilateral mandibular DO the cartilaginous alterations are most prominent on the distracted side where the pressure created against the TMJ is greatest 8 .…”

The Effect of Distraction on the Temporomandibular Joint

“…No evidence of vascular necrosis, microfracture or cystic degeneration was noted. These finding are consistent with those reported for a sheep model (31). In this study distraction osteogenesis was performed in the mandible in seventeen growing A sheep.…”

Stress Distribution in Mandible and Temporomandibular Joint by Mandibular Distraction: A 3-Dimensional Finite-element Analysis

“…The influence of distraction osteogenesis on the TMJ has been reported in animal experiments using dogs and sheep 10,15,24,26) . Thurmuller, using a minipig, reported that changes were more severe at faster distraction rates (4 mm/day) and tended to resolve during neutral fixation when a rate of 1 mm/day was used 29) .…”