The Effect of Ginseng Flower Extract on the Skin Ageing Inhibition

Abstract

In this study, ingredients were analyzed to see if ginseng flower extracts help suppress skin aging, and physiological activities were tested to evaluate antioxidant effects, cytotoxicity, anti-inflammatory effects, and cell regeneration effects. The GC/MS component analysis showed that the highest content was sucrose (18.72%) which is a polysaccharide used as a moisturizer, followed by Decanoic acid and 2ethyl hexyl ester (10.01%), and the phenolic compound 2-Methoxy-4-vinyl phenol (3.69%). Antioxidant (DPPH) measurements also confirmed that when the control Vit.C shows 97% dissipation, ginseng flower extract increases in concentration from 0.25 mg/mL to 39.15±1.25%, 0.5 mg/mL to 49.44±0.99%, and 1 mg/mL to 71.91±5.67%. The cytotoxicity assessment showed that ginseng flower extracts were safe and not toxic material with a survival rate of 89.1±79.76% at 0.25 mg/mL, 86.8±84.08% at 0.5 mg/mL, and 85.48±79.56% at 1 mg/mL. In addition, ginseng flower extracts were found to have an anti-inflammatory effect as they concentratedependent inhibition of NO production at 24.41±6.30 μM at 0.25 mg/mL, 23.95±9.69 μM at 0.5 mg/mL, and 14.37±10.34 μM at 1 mg/ mL. According to the results of observing the cell migration rate by concentration (0.25%, 0.5%, 1%) of ginseng flower extracts with an Inverted microscope, the empty space of the scratch narrows as the concentration of the extract increases, and the cell proliferates actively, which shows that ginseng flower extracts promote skin regeneration. Through this experiment, ginseng flower extracts are safe without toxicity and have antioxidant activity, anti-inflammatory effect, and cell regeneration effectiveness of the skin, which has inhibitory skin aging. As a result, ginseng flower extracts will be used as natural cosmetics to help prevent skin aging, although more clinical experiments will be needed in the future, and research on various application methods will continue.

Effects of Skin Inflammation Related Cytokine on Mentha arvensis Ethanol Extract (MT)

“…만성피부질환에서 국소 스테로이드 치료제를 장기간 사 *Corresponding author: Won-Jin Baek Tel : +82-51-540-7687 E-mail : beauty@kwu.ac.kr 접수일(2023년 6월 13일)/수정일(2023년 7월 13일)/채택일(2023년 7월 27일) 용 시 발생하는 부작용을 줄이기 위해 일시적으로 사용을 중단 하거나 보습제를 병용해야 한다. 박하(Mentha arvensis, cornmint)는 꿀풀과(Lamiaceae)에 속 하는 다년생 식물로 한국, 중국, 시베리아 습지에 서식하며, 한 국에서는 Mentha arvensis L.로, 중국에서는 M. haploxalys Briq 로 기원을 규정하고 있다 (Kim et al, 2003) (Bae, 2000). 효능으로 해열작용, 소염작용, 담즙분비 촉진 및 위장 평활근 억제 작용, 호흡 기도의 점액분비 증가, 자궁수 축 등에 효과적인 것으로 알려진 천연물이다 (Choi, 2007) (2) RNA 추출 카인의 활성을 증가시켜 피부염증을 초래한다 (Lee et al, 2012).…”