The effect of formulation variables on the stability of nebulized aviscumine

Phase behavior studies of quaternary systems containing N-lauroyl-N-methylglucamide/alcohol/alkane/water

“…(9) are K and I , respectively, then A S values of quaternary systems MEGA-12/1-butanol/alkane/brine (5% NaCl) in Fig. 2 can be calculated by (10) …”

“…In recent years, much attention has been paid to the nonionic green surfactants N -acyl-N -alkylglucamides (NAGAs), due to their compatibility, relatively low toxicity, minimal environmental impact, and synergistic effects when combined with other surfactants [1][2][3][4][5][6][7][8][9][10]. These surfactants can be synthesized from carbohydrate raw materials: sucrose, glucose, and sorbitol, which are available on the world market in large quantities and at competitive prices [11][12][13][14].…”

Antibacterial Efficacy of Inhalable Levofloxacin-Loaded Polymeric Nanoparticles Against E. coli Biofilm Cells: The Effect of Antibiotic Release Profile

“…Antibiotics have also been encapsulated into polymeric nanoparticles for inhaled tuberculosis therapy (17,18). Lastly, inhaled nanoparticle formulations of antifungal agents, immunosuppressant agents, and therapeutic proteins, have also been investigated (19)(20)(21).…”

Nebulization of single-chain tissue-type and single-chain urokinase plasminogen activator for treatment of inhalational smoke-induced acute lung injury

“…The degradation of nebulized protein is reportedly associated with air-liquid interfaces and temperature changes (34). Several studies report that proteins degrade during nebulization using ultrasonic nebulizers (80, 81). For example, Aviscumin, a recombinant mistletoe lectin lost 50% of its activity after nebulization using an ultrasonic nebulizer (80).…”