The effect of environmental temperature on exercise-dependent release of brain-derived neurotrophic factor

Abstract

Brain-derived neurotrophic factor (BDNF) is a biomarker of cognitive function that is released into the blood stream following exercise, and cognitive function is impaired by environmental temperatures that are hot and cold. Purpose: To evaluate the exercise-dependent release of BDNF in different environmental temperatures. Methods: Recreationally trained males each completed three trials consisting of cycling for 1 h at 60% W max at three different temperatures: 33 C (hot), 7 C (cold), and 20 C (moderate room temperature). Blood was taken from the antecubital vein preexercise, immediately post-exercise, and 3 h post-exercise. Respiratory gases were collected periodically throughout exercise and recovery. Results: BDNF was elevated immediately following an exercise bout (1711 § 766 pg·ml ¡1 ) regardless of temperature from pre-exercise (1257 § 653 pg·ml ¡1 , p D 0.001) and returned to basal levels following 3 h of recovery (1289 § 650 pg·ml ¡1 , p D 0.786). There was no effect (p > 0.05) of temperature on BDNF following the exercise bout. Plasma glucose was elevated in hot (6.2 § 0.9 mmol) over cold (5.3 § 0.6 mmol, p D 0.035) and moderate room temperature (5.2 § 0.5, p D 0.008). VO 2 was elevated during exercise in hot (3.01 § 0.

An 18-hole round of golf acutely elevates serum interleukin-6 and brain-derived neurotrophic factor concentration - a pilot study

“…It should be noted that the acute BDNF response was modest (~20% increase) compared to several other exercise studies. For instance, 1 h of cycling at 55-60% peak oxygen uptake results in a ~50% increase in serum BDNF concentration 30,31) . In contrast, the BDNF response in the present study is more in line with shorter duration (i.e.…”

Intestinal damage following short-duration exercise at the same relative intensity is similar in temperate and hot environments

“…Snipe et al (Snipe et al 2016;Snipe et al 2018a) have reported a dose response in post-exercise intestinal damage, as measured by I-FABP, with increasing environmental temperature from 22°C to 30°C and 22°C to 35°C. While the damage may in part be attributed to increasing ambient temperature, participants were running at the same absolute treadmill speed during each trial and as such exercise intensity may have differed in the hot versus temperate conditions given the possible increased physiological strain and metabolic cost of exercising in the heat (No and Kwak 2016;Collins et al 2017). In the presence of cardiovascular drift when exercising in the heat at a set workload, heart rate remains a reliable indicator of relative exercise intensity (Wingo 2015) and Snipe et al (Snipe et al 2018a;Snipe et al 2018b) reported significantly higher heart rates (and ratings of perceived exertion) when exercising at the same absolute intensity in 30°C and 35°C compared to 22°C, indicating greater physiological strain when exercising it the heat .…”