The effect of environmental hypercapnia and size on nitrite toxicity in the striped catfish (Pangasianodon hypophthalmus)

Hvas, Malthe; Damsgaard, Christian; Gam, Le Thi Hong; Hương, Đỗ Thị Thanh; Frank, Jason; Bayley, Mark

doi:10.1016/j.aquatox.2016.04.020

Cited by 23 publications

(18 citation statements)

References 38 publications

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“…Previous studies in P. hypophthalmus have shown that blood pH equilibrates rapidly when the PCO 2 of the ambient water changes 20, 50 . In water with a PCO 2 of 34 mmHg, blood pH fell rapidly from 7.8 to 7.3 at 27 °C.…”

Section: Discussionmentioning

confidence: 93%

Lactate provides a strong pH-independent ventilatory signal in the facultative air-breathing teleost Pangasianodon hypophthalmus

Thomsen

Wang

Milsom

et al. 2017

Sci Rep

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Fish regulate ventilation primarily by sensing O2-levels in the water and arterial blood. It is well established that this sensory process involves several steps, but the underlying mechanisms remain frustratingly elusive. Here we examine the effect of increasing lactate ions at constant pH on ventilation in a teleost; specifically the facultative air-breathing catfish Pangasianodon hypophthalmus. At lactate levels within the physiological range obtained by Na-Lactate injections (3.5 ± 0.8 to 10.9 ± 0.7 mmol L−1), gill ventilation increased in a dose-dependent manner to levels comparable to those elicited by NaCN injections (2.0 µmol kg−1), which induces a hypoxic response and higher than those observed in any level of ambient hypoxia (lowest PO2 = 20 mmHg). High lactate concentrations also stimulated air-breathing. Denervation of the first gill arch reduced the ventilatory response to lactate suggesting that part of the sensory mechanism for lactate is located at the first gill arch. However, since a residual response remained after this denervation, the other gill arches or extrabranchial locations must also be important for lactate sensing. We propose that lactate plays a role as a signalling molecule in the hypoxic ventilatory response in fish.

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Section: Discussionmentioning

confidence: 93%

Lactate provides a strong pH-independent ventilatory signal in the facultative air-breathing teleost Pangasianodon hypophthalmus

Thomsen

Wang

Milsom

et al. 2017

Sci Rep

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“…() and Hvas et al . () reported that smaller fish are less sensitive to nitrite than larger individuals. Hvas et al .…”

Section: Toxicitymentioning

confidence: 99%

“…Another possible explanation is that, unlike juveniles or adults, the early development stages do not possess fully developed gills, and their respiration therefore occurs mostly through their skin, lowering the importance of oxygen transport through blood (Bartlett & Neumann 1998). Atwood et al (2001) and Hvas et al (2016) reported that smaller fish are less sensitive to nitrite than larger individuals. Hvas et al (2016) showed that smaller fish had a higher capacity for detoxifying nitrite to nitrate than larger fish.…”

mentioning

confidence: 99%

“…Atwood et al (2001) and Hvas et al (2016) reported that smaller fish are less sensitive to nitrite than larger individuals. Hvas et al (2016) showed that smaller fish had a higher capacity for detoxifying nitrite to nitrate than larger fish. However, in any case, it was not clear whether both studied groups were juveniles or whether the larger fish were already adult, that is whether it is size or both size and stage dependent effect.…”

mentioning

confidence: 99%

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Toxic effects of nitrite on freshwater organisms: a review

Kroupová

Valentová

Svobodová

et al. 2016

Reviews in Aquaculture

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High nitrite concentrations may occur mainly in recirculating aquaculture systems, but can also be found under certain conditions in natural waters. Among studied freshwater organisms, molluscs and worms followed by fish are the most resistant to nitrite. On the other hand, crustaceans and aquatic insects followed by amphibians are the most sensitive. Wide interspecific differences in nitrite susceptibility can be found within freshwater insects, crustaceans and amphibians. Chloride concentration in water is supposed to be the most important factor influencing nitrite toxicity. Generally, a positive chloride effect on nitrite toxicity reduction can be expected in all aquatic animals (or their early stages) employing gills for breathing and ion exchange. This phenomenon has already been observed in an amphipod (Eulimnogammarus toletanus, Pinkster & Stock), a planarian (Polycelis felina, Dalyell), two species of crayfish, several fish species and in amphibians in early development stages. A relatively huge amount of data on nitrite effects is available for fish, but other freshwater organisms were less frequently studied. Information on chronic effect of nitrite is nearly completely missing.

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“…[ 49 ] Apical NHE appears in most species, while apical VHA is found only in limited species. Selected species are hagfish ( Myxine glutinosa ), [ 50 ] lamprey ( Lethenteron reissneri ), shark ( Mustelus antarcticus ), [ 51 ] sturgeon ( Acipenser transmontanus ), [ 52 ] eel ( Anguilla anguilla ), [ 53 ] catfish ( Pangasianodon hypophthalmus ), [ 54 ] loach ( Misgurnus anguillicaudatus ), [ 16 ] Osorezan dace ( Tribolodon hakonensis ), [ 41 ] goldfish ( Carassius auratus ), [ 55 ] carp ( Cyprinus carpio ), [ 35 ] Lake Candidus (LC) dace ( Candidia barbata ), rainbow trout ( Oncorhynchus mykiss ), [ 27–29 ] tilapia ( Oreochromis mossambicus ), [ 56 ] medaka ( Oryzias latipes ), [ 26 ] , killifish ( Fundulus heteroclitus ), [ 57 ] mudskipper ( Periophthalmodon schlosseri ), [ 30 ] and pufferfish. ( Takifugu rubripes ).…”

Section: Loss Of the Vha Trait During Fish Evolutionmentioning

confidence: 99%

Did Acidic Stress Resistance in Vertebrates Evolve as Na⁺/H⁺ Exchanger‐Mediated Ammonia Excretion in Fish?

et al. 2020

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How vertebrates evolved different traits for acid excretion to maintain body fluid pH homeostasis is largely unknown. The evolution of Na + /H + exchanger (NHE)-mediated NH 4 + excretion in fishes is reported, and the coevolution with increased ammoniagenesis and accompanying gluconeogenesis is speculated to benefit vertebrates in terms of both internal homeostasis and energy metabolism response to acidic stress. The findings provide new insights into our understanding of the possible adaptation of fishes to progressing global environmental acidification. In human kidney, titratable H + and NH 4 + comprise the two main components of net acid excretion. V-type H + -ATPase-mediated H + excretion may have developed in stenohaline lampreys when they initially invaded freshwater from marine habitats, but thistrait is lost in most fishes. Instead, increased reliance on NHE-mediated NH 4 + excretion is gradually developed and intensified during fish evolution.Further investigations on more species will be needed to support the hypothesis. Also see the video abstract here https://youtu.be/vZuObtfm-34.

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The effect of environmental hypercapnia and size on nitrite toxicity in the striped catfish (Pangasianodon hypophthalmus)

Cited by 23 publications

References 38 publications

Lactate provides a strong pH-independent ventilatory signal in the facultative air-breathing teleost Pangasianodon hypophthalmus

Lactate provides a strong pH-independent ventilatory signal in the facultative air-breathing teleost Pangasianodon hypophthalmus

Toxic effects of nitrite on freshwater organisms: a review

Did Acidic Stress Resistance in Vertebrates Evolve as Na⁺/H⁺ Exchanger‐Mediated Ammonia Excretion in Fish?

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The effect of environmental hypercapnia and size on nitrite toxicity in the striped catfish (Pangasianodon hypophthalmus)

Cited by 23 publications

References 38 publications

Lactate provides a strong pH-independent ventilatory signal in the facultative air-breathing teleost Pangasianodon hypophthalmus

Lactate provides a strong pH-independent ventilatory signal in the facultative air-breathing teleost Pangasianodon hypophthalmus

Toxic effects of nitrite on freshwater organisms: a review

Did Acidic Stress Resistance in Vertebrates Evolve as Na+/H+ Exchanger‐Mediated Ammonia Excretion in Fish?

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Did Acidic Stress Resistance in Vertebrates Evolve as Na⁺/H⁺ Exchanger‐Mediated Ammonia Excretion in Fish?