The effect of eight weeks of exercise on knee adduction moment in early knee osteoarthritis – a pilot study

Abstract

This study indicates that peak knee adduction moment could be reduced by supervised, individualized exercise in middle-aged patients presenting early signs of knee osteoarthritis, suggesting further investigation of this area. Peak adduction moment during one-leg rise seems to be more sensitive to deviations and change than peak adduction moment during gait in this population.

Change in serum COMP concentration due to ambulatory load is not related to knee OA Status

“…The perceived benefits of these programs include reduction in pain, improved function, and altered joint load. 21,22 However, the effects of such programs on turnover of cartilage constituents including COMP are largely unknown. Serum COMP concentration in patients with knee OA increased during strengthening exercise and returned to baseline within 24 h. 10 In the current study, serum COMP concentrations increased similarly in patients with knee OA and in age-matched control subjects during a controlled walking exercise.…”

Reduction in knee adduction moment via non-invasive biomechanical training: A longitudinal gait analysis study

“…Biomechanical interventions focusing on foot center of pressure (COP) manipulation, agility, and perturbation training have been suggested for the treatment of knee OA (Bar-Ziv et al, 2010; Elbaz et al, 2010;Fitzgerald et al, 2002;Hurley and Scott, 1998;Thorstensson et al, 2007). Such interventions were reported to facilitate superior levels of functional activity, to reduce pain, and to influence spatiotemporal parameters during gait (Bar-Ziv et al, 2010;Elbaz et al, 2010;Erhart et al, 2010;Fitzgerald et al, 2002;Roddy et al, 2005;Thorstensson et al, 2007).…”

“…Such interventions were reported to facilitate superior levels of functional activity, to reduce pain, and to influence spatiotemporal parameters during gait (Bar-Ziv et al, 2010;Elbaz et al, 2010;Erhart et al, 2010;Fitzgerald et al, 2002;Roddy et al, 2005;Thorstensson et al, 2007). One such treatment modality is the AposTherapy, a customized program utilizing daily treatment with a novel foot-worn biomechanical device capable of modifying the foot's COP and thus altering the KAM.…”

A Biomechanical Perspective on Physical Therapy Management of Knee Osteoarthritis

“…15,159 Evidence in support of this notion has been provided by recent pilot studies of combined neuromuscular training that includes balance, perturbation, agility, plyometrics, and endurance activities along with traditional lowerlimb muscle strengthening exercises to lead to positive joint-protective reductions in loading across the knee joint. 143,193 JOINT INSTABILITY AND KNEE OA E pisodic reports of knee joint instability (eg, giving way, buckling, or the shifting of arthritic knees) during activities of daily living are common and represent a significant cause of functional limitation in individuals with knee OA. 58,198 The sensation of joint instability is most likely associated with abnormal or excessive translations of the articular surfaces that subject the knee joint to harmful shear forces and accelerated rates of disease progression.…”