The Effect of Disodium Cromoglycate on Airway Conductance and on Serum Cortisol and Serum Reagins in Asthma*

Holmgren, A.; Olsson, Anders; Svanborg, Nils; Wide, Leif

doi:10.1111/j.1398-9995.1972.tb01640.x

Cited by 4 publications

(2 citation statements)

References 16 publications

(12 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The decrease in sensitivity varied during long-term treatment with Lomudal, which may have paralleled reduction in dosage of other drugs. It is quite obvious that Lomudal has a good effect in this test, but that it does not totally inhibit the allergic reaction (2).…”

mentioning

confidence: 93%

Desensitization During Lomudal Treatment

Svanborg¹

1975

Allergy

View full text Add to dashboard Cite

mentioning

confidence: 93%

Desensitization During Lomudal Treatment

Svanborg¹

1975

Allergy

View full text Add to dashboard Cite

“…However, the reported results on such measurements lack agreement (Newcomb & DeVald, 1969;Ryley and Brogan, 1968;Brogan et al, 1971;Heilpern & Rebuck, 1972;Smith, Bellanti & Chanock, 1967;Ishizaka & Newcomb, 1970;Hobday, Cake & Turner, 1971). Disodium cromoglycate (DSCG), with few exceptions, affords 'protective' effects in asthma, and apparently reduces the incidence of coughing and the secretion of bronchial mucus (Holmgren et al, 1972). Heilpern & Rebuck (1972) reported that the albumin content was significantly higher in the sputum of asthmatic patients than in non-asthmatics, and that DSCG therapy reduced the level of sputum albumin in the asthmatics to that found in the control non-asthmatic subjects.…”

Section: Introductionmentioning

confidence: 99%

The effect of disodium cromoglycate (DSCG) on the levels of albumin and the immunoglobulins IgA, IgG, IgM and IgE in sputum

Turner

Rebuck

1975

Clin Experimental Allergy

View full text Add to dashboard Cite

Summary Sputum samples from control subjects with cardiac disease and from patients with asthma were assayed for albumin content and immunoglobulins IgA, IgG, IgM and IgE. The asthmatics were divided into three groups: one group had received disodium cromoglycate (DSCG) for at least 48 hr prior to sampling, another group was sampled daily after commencing DSCG therapy and the third group were not taking DSCG. Albumin and immunoglobulins accounted for approximately 8% of the total sputum proteins in each of the four groups of subjects. There was no significant difference in the mean sputum levels of albumin or the immunoglobulins, when expressed as a percentage of total sputum proteins, between the subjects in each group. However, the ratios of IgA/albumin and IgA/IgG in the asthmatic group receiving DSCG were significantly lower than the corresponding ratios in sputa from both asthmatics and control subjects with cardiac disease. The sputum IgE levels tended to be higher in the asthmatics than in the control group, but DSCG therapy had little effect upon sputum IgE levels.

show abstract

Cromolyn Sodium (Disodium Cromoglycate) Prophylaxis

Falliers

1975

Pediatric Clinics of North America

View full text Add to dashboard Cite

The Effect of Disodium Cromoglycate on Airway Conductance and on Serum Cortisol and Serum Reagins in Asthma*

Cited by 4 publications

References 16 publications

Desensitization During Lomudal Treatment

Desensitization During Lomudal Treatment

The effect of disodium cromoglycate (DSCG) on the levels of albumin and the immunoglobulins IgA, IgG, IgM and IgE in sputum

Cromolyn Sodium (Disodium Cromoglycate) Prophylaxis

Contact Info

Product

Resources

About