The Effect of Diode Laser on Planktonic<i>Enterococcus faecalis</i>in Infected Root Canals in an<i>Ex Vivo</i>Model

Cretella, Gilda; Lajolo, Carlo; Castagnola, Raffaella; Somma, Francesco; Inchingolo, Maria Teresa; Marigo, Luca

doi:10.1089/pho.2016.4174

Cited by 6 publications

(1 citation statement)

References 33 publications

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“…For treatment purposes, MB has antimicrobial properties [21] and has been used as an antidote in emergency and critical care [6,22,23]. Additionally, it can be administered as an adjuvant therapy, enhancing the outcomes of selected drugs or procedures [24][25][26][27]. MB has also been used as the main treatment strategy, being administered alone or combined with other therapies [4][5][6][7]10,12,16,22,[28][29][30][31][32][33][34][35][36] Studies evaluating effective drugs for health conditions are considered of crucial importance in public health.…”

Section: Introductionmentioning

confidence: 99%

Methylene Blue for the Treatment of Health Conditions: a Scoping Review

Galvan

Borsoi

Julek

et al. 2021

Braz. arch. biol. technol.

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studies evaluating effective drugs for health conditions are of crucial importance for public health. Methylene blue (MB) is an accessible synthetic drug that presents low toxicity and has been used in several health areas due to its effectiveness. Objective: this scoping review aims to provide a comprehensive overview of relevant research regarding the use of MB for the treatment of health conditions. Methods: a fivestage framework Arksey and O'maley scoping review was conducted. The literature was searched in Cochrane Library database using Mesh term "methylene blue". Data were collected by two independent reviewers and submitted to descriptive synthesis. Results: The search resulted in 429 records, from which 16 were included after exclusion criteria were applied. The therapeutic use of MB was identified for acute conditions (malaria and septic shock), chronic conditions (discogenic back pain, bipolar disorder, refractory neuropathic pain, and post-traumatic stress disorder), and postoperative care (vasoplegic syndrome, and pain after haemorrhoidectomy, lumbar discectomy, and traumatic thoracolumbar fixation). Conclusion: there is much evidence emerging from clinical trials about the therapeutic use of MB for acute, chronic, and HIGHLIGHTS  This scoping review summarizes the findings of clinical trials using methylene blue (MB) for the treatment of various health conditions.  This research method allowed mapping main findings, clarifying research topics, and identifying gaps in the literature.

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Section: Introductionmentioning

confidence: 99%

Methylene Blue for the Treatment of Health Conditions: a Scoping Review

Galvan

Borsoi

Julek

et al. 2021

Braz. arch. biol. technol.

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The efficacy of 2780 nm Er,Cr;YSGG and 940 nm Diode Laser in root canal disinfection: A randomized clinical trial

Fahim,

Ghali,

Hashem

et al. 2024

Clin Oral Invest

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Objectives Effective disinfection of the root canals is the cornerstone of successful endodontic treatment. Diminishing the microbial load within the root canal system is crucial for healing in endodontically treated teeth. The aim of this study was to evaluate the effect of 2780 nm Er,Cr:YSGG and 940 nm diode lasers on the eradication of microorganisms from single-rooted teeth with asymptomatic apical periodontitis. Materials and Methods Thirty participants conforming to the inclusion criteria were randomly divided into 3 groups according to the disinfection protocol used; Conventional group: 2.5% Sodium Hypochlorite (NaOCl) and 17% EDTA solution NaOCl/EDTA, Dual laser group: 2780 nm Erbium, chromium: yttrium scandium-gallium-garnet (Er,Cr:YSGG) laser and 940 nm diode laser Er,CrYSGG/Diode, and Combined group: 17% EDTA and 940 nm diode laser EDTA/Diode. Bacterial samples were collected before and after intervention. The collected data were statistically analyzed using Friedman’s test and Kruskal–Wallis test (P ≤ 0.05). Results The results of the study showed that both dual laser Er,CrYSGG/Diode and combined laser EDTA/Diode groups showed significantly less mean Log10 CFU/ml of aerobic and anaerobic bacterial counts than the conventional NaOCl/EDTA group. Conclusions In this study we evaluated in vivo the bactericidal efficacy of three disinfection protocols for endodontic treatment of single-rooted teeth with apical periodontitis. The results indicated that both dual laser Er,CrYSGG/Diode and combined laser EDTA/Diode groups provide superior bactericidal effect compared to the conventional NaOCl/EDTA group. Clinical relevance The integration of lasers into root canal disinfection protocols has demonstrated significant bacterial reduction which might promote healing and long-term success.

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Rationale for using a double-wavelength (940 nm + 2780 nm) laser in endodontics: literature overview and proof-of-concept

Martins

Franzen

Depraet³

et al. 2018

Laser Dent Sci

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Aim The goal of endodontic research is to report interventions, techniques or protocols that are most likely to deliver the outcomes that are of most interest to both clinicians and patients. The development of a double-wavelength laser delivered concomitantly and through the same radial firing tip (RFT) may provide a unique combination of beneficial properties that may clinically surpass all previously reported laser-assisted protocols. The aim is to present a rational literature overview that could support the adoption of simultaneous use 2780 and 940 nm wavelengths for smear layer removal and disinfection respectively. Methods In order to provide relevant clinical data, two distinct clinical cases of relatively high endodontic complexity are reported with 1-year follow-up.Results The results of both clinical cases show the immediate remission of symptoms, absence of clinical complications and complete radiographic healing. Conlusions Together with the available amount of literature that could support the effectiveness of these two wavelengths to remove SL and to achieve deep dentin disinfection, it is possible to expect that this innovative combination of lasers delivered by RFT may be of high clinical relevance in the near future.

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The Effect of Diode Laser on PlanktonicEnterococcus faecalisin Infected Root Canals in anEx VivoModel

Abstract: Evidence indicates that the diode laser was not more effective than sodium hypochlorite in reducing free bacteria.

Cited by 6 publications

References 33 publications

Methylene Blue for the Treatment of Health Conditions: a Scoping Review

Methylene Blue for the Treatment of Health Conditions: a Scoping Review

The efficacy of 2780 nm Er,Cr;YSGG and 940 nm Diode Laser in root canal disinfection: A randomized clinical trial

Rationale for using a double-wavelength (940 nm + 2780 nm) laser in endodontics: literature overview and proof-of-concept

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