The Effect of Different Types of Bariatric Surgery on Metabolic and Hormonal Parameters in Rats with a Decompensated Form of Type II Diabetes Mellitus

Kornyushin, O. V.; Bakhtyukov, A. A.; Zorina, I. I.; Toropova, Yana; Derkach, K. V.; Берко, О. М.; Todosenko, M. N.; Litvinova, L. S.; Шпаков, А. О.; Galagudza, M. M.

doi:10.1134/s2079057019030081

Cited by 3 publications

(3 citation statements)

References 24 publications

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“…This thesis is proved by the established effects of displacement of the distal segment of the small intestine in the experiment, i.e. the increase in the number and secretory activity of L-cells of the displaced segment of the intestine, increase in the secretion of glucagonlike peptide 1 and -2 (GLP-1, GLP-2), peptide tyrosine-tyrosine (PYY), increase in the mass of β-cells of the pancreas, decrease in their apoptosis and increase in insulin production, and increase in glucose tolerance [38,39,40].…”

Section: Effect Of Bariatric Operations On Glucose Metabolismmentioning

confidence: 99%

Alternative ways to correct poor glucose metabolism in patient with diabetes mellitus

Sevastyanov¹,

Turgunov²,

Faure³

et al. 2021

J CLIN MED KAZ

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Section: Effect Of Bariatric Operations On Glucose Metabolismmentioning

confidence: 99%

Alternative ways to correct poor glucose metabolism in patient with diabetes mellitus

Sevastyanov¹,

Turgunov²,

Faure³

et al. 2021

J CLIN MED KAZ

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“…Several factors such as age, gender, genetic, obesity phenotype, lifestyle factors, as well as the type of bariatric surgery influence the percentage weight loss after surgery [ 4 ]. Laparoscopic sleeve gastrectomy (LSG), Roux-en-Y gastric bypass (RYGB), and more recently one-anastomosis gastric bypass (OAGB) have been the most popular and bariatric operations in recent years, resulting in different weight loss at different times post-surgery [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Bariatric Surgeries, from Weight Loss to Weight Regain: A Retrospective Five-Years Cohort Study

Hatami,

Pazouki,

Hosseini-baharanchi

et al. 2023

Obes Facts

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Introduction: Bariatric surgery may lead to unsatisfactory weight loss, weight loss plateau, and even weight regain after various types of surgery. Despite the numerous studies, the mid-term results of surgery, after repetitive weight fluctuations remain a major concern. The aim of the present study was to determine the key time points of weight changes after three types of bariatric procedures, as well as to determine 5-year weight loss outcome after surgery. Methods: This is a retrospective cohort study including patients with morbid obesity conducted in the Minimally Invasive Surgery Research Center. The patients underwent one of the three types of bariatric surgeries including laparoscopic sleeve gastrectomy (LSG), Roux-en-Y gastric bypass (RYGB), and one-anastomosis gastric bypass (OAGB), who had been followed up for weight loss trend during 5 years postoperatively. Results: The mean excessive weight loss (%EWL) and total weight loss (%TWL) of 2,567 participants with obesity (mean age = 39.03, mean BMI = 45.67) in the first 6 months after surgery was independent of the type of surgery (p > 0.05). OAGB and RYGB showed significantly higher weight loss compared to LSG in ninth and 24th month after surgery, respectively (p < 0.05). The 5 years %WL could be comparable with %WL in 6, 9, and 12 months after LSG, RYGB, and OAGB, respectively. Conclusion: OAGB provides the fastest and highest %EWL and %TWL, while LSG induced the earliest and largest weight plateau and weight regain during 5-years post-surgery. The pattern of early weight loss could predict the mid-term outcome of bariatric surgery. So, early identification of suboptimal weight loss could enhance long-term weight loss.

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“…Several factors such as age, gender, genetic, obesity phenotype, lifestyle factors, and also the type of bariatric surgery are in uenced on the percentage of excess weight loss (%EWL) and time after surgery (4). Laparoscopic sleeve gastrectomy (LSG), Roux-en-Y gastric bypass (RYGB), and one-anastomose gastric bypass (OAGB) are the most popular and successful bariatric surgeries in recent years resulted in the different %EWL at different times after surgery (5).…”

Section: Introductionmentioning

confidence: 99%

Key Time Points After Bariatric Surgery, From Weight Loss To Weight Regain: Long-Term Retrospective Cohort Study

Hatami

Pazouki

Hosseini-Baharanchi

et al. 2021

Preprint

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Background and Objective: Bariatric surgery may lead to an unsuccessful weight loss, weight loss plateau, and even weight regain in different time points after various types of surgery. Despite the numerous studies investigated bariatric surgery-induced weight loss, the long-term results of surgery, after repetitive weight fluctuations, is not really clear and remains as one of the most important concerns. The aim of the present study was to determine the key time points of weight changes after three types of bariatric surgery, and the estimation of five-year weight loss after surgery. Setting: This is a retrospective cohort study including patients with morbid obesity conducted in the obesity clinic of Minimally Invasive Surgery Research Center of Iran University of Medical Sciences. Methods The subjects underwent one of the three types of bariatric surgeries including laparoscopic sleeve gastrectomy (LSG), Roux-en-Y gastric bypass (RYGB), and one anastomosis gastric bypass (OAGB) which had been followed up to five years after surgery. The percentage lost to follow-up was 34% until five-year after surgery. Results The mean %EWL a total of 2567 morbid obese participants (mean age=39.03, mean BMI=45.67) in the first six months after surgery was independent of the type of surgery. Ninth and 24th month after surgery were the times that OAGB and then RYGB induced weight loss sped up rather than LSG, respectively. Weight plateau and weight regain were initiated earlier (at 18th month) and more (18.23% of maximum EWL %) in LSG in the period of five years. The %EWL in time intervals of 3-6, 6-9, and 9-12 months after LSG, RYGB, and OAGB, respectively; could estimate the long-term five years %EWL after surgery. Conclusion OAGB provides the fastest and highest %EWL, and LSG induced the earliest and most weight plateau and weight regain during five years interval post-surgery. The pattern of early weight loss could predict the long-term outcome of bariatric surgery. So early identification of suboptimal weight loss could allow consideration of earlier postoperative intervention to enhance long-term weight loss.

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The Effect of Different Types of Bariatric Surgery on Metabolic and Hormonal Parameters in Rats with a Decompensated Form of Type II Diabetes Mellitus

Cited by 3 publications

References 24 publications

Alternative ways to correct poor glucose metabolism in patient with diabetes mellitus

Alternative ways to correct poor glucose metabolism in patient with diabetes mellitus

Bariatric Surgeries, from Weight Loss to Weight Regain: A Retrospective Five-Years Cohort Study

Key Time Points After Bariatric Surgery, From Weight Loss To Weight Regain: Long-Term Retrospective Cohort Study

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