The effect of different dietary inclusion levels of rutin (a flavonoid) on some liver enzyme activities and oxidative stress indices in rainbow trout,<i>Oncorhynchus mykiss</i>(Walbaum) exposed to Oxytetracycline

Nazeri, Sepideh; Farhangi, Mehrdad; Modarres, Saghar

doi:10.1111/are.13257

Cited by 38 publications

(20 citation statements)

References 23 publications

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“…OTC‐induced oxidative stress has been well documented in fish. In rainbow trout, Yonar (), Yonar et al () and Nazeri, Farhangi, and Modarres () reported decrease in SOD, CAT and GPx and increase in GST activity and MDA content following 75 mg/kg OTC administration, which are in line with the present results. On the other hand, thyme treatment alone stimulated the antioxidant enzymes’ activity and decreased MDA levels; it also suppressed OTC‐induced changes in these parameters.…”

Section: Discussionsupporting

confidence: 91%

Beneficial effects of thyme (Thymus vulgaris) extract on oxytetracycline-induced stress response, immunosuppression, oxidative stress and enzymatic changes in rainbow trout (Oncorhynchus mykiss)

Hoseini

Yousefi

2018

Aquacult Nutr

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The aim of the present study was to investigate the effects of thyme extract (TE) and oxytetracycline (OTC) on rainbow trout (Oncorhynchus mykiss) stress response, immune parameters, oxidative stress and enzymatic changes. The fish were assigned into eight treatments receiving diets with OTC (0 and 2.5 g/kg) and TE (0, 5, 10 and 20 g/kg) for 2 weeks. Thereafter, serum characteristics and gut oxidative status were evaluated. OTC significantly increased serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities, and cortisol and glucose levels; however, TE significantly suppressed these changes. OTC significantly decreased, but TE significantly increased gut catalase (CAT) and glutathione peroxidase (GPx) activities.OTC significantly decreased gut superoxide dismutase (SOD) and increased gut glutathione-s-transferase (GST) activities, malondialdehyde (MDA) content and blood monocyte percentage; TE significantly mitigated these changes. TE significantly increased serum total protein, total Ig, lysozyme and ACH50, and blood WBC; however, OTC significantly decreased serum lysozyme and ACH50 activities and blood WBC and neutrophil percentage. In conclusion, OTC administration causes immunosuppression, which might be related to deterioration of fish health. TE augments trout innate immune and antioxidant status and is capable to counteract OTC-induced health and immune deterioration. K E Y W O R D Shealth, innate immune, oxytetracycline, thyme, trout | 299 HOSEINI aNd YOUSEFI

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Section: Discussionsupporting

confidence: 91%

Beneficial effects of thyme (Thymus vulgaris) extract on oxytetracycline-induced stress response, immunosuppression, oxidative stress and enzymatic changes in rainbow trout (Oncorhynchus mykiss)

Hoseini

Yousefi

2018

Aquacult Nutr

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“…ALT and AST are two important indexes, which can reflect the function of liver. Under normal conditions, the activities of transaminases in serum remain low, unless the tissues is damaged or lesions (Nazeri, Farhangi, & Modarres, ; Santhoshkumar et al, ). When the pathological changes occur, the necrosis of tissue cells leads to the release of a large number of transaminases into blood, which would cause the increase of the contents of ALT and AST (Kalhoro et al, ; Li et al, ).…”

Section: Discussionmentioning

confidence: 99%

Effects of dietary n-3HUFA on juvenile white shrimp, Litopenaeus vannamei: Growth, feed utilization, antioxidant enzymes activities and fatty acid compositions

Yang

Tan

et al. 2019

Aquac Res

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Present study investigates the effects of n-3 high-unsaturated fatty acid (n-3HUFA) levels on growth performance, antioxidant enzymes activities and fatty acid compositions of juvenile Litopenaeus vannamei. These represented seven iso-nitrogenous and iso-lipidic diets. Analysed n-3HUFA concentrations were 0.16% (control), 0.48%, 0.74%, 1.39%, 2.39%, 2.92% and 3.44% respectively. A total of 840 juvenile L. vannamei were randomly stocked into 21 0.5 m 3 tanks for 56 days. A significant increase (p < 0.05) was observed from 0.16% to 0.74% n-3HUFA and a decrease when n-3HUFA was above these levels in weight gain rate (WGR) and specific growth rate. Total cholesterol, triglyceride and low-density lipoprotein in serum showed a significant decrease, highdensity lipoprotein showed a significant increase (p < 0.05). Phenoloxidase activity in serum and sodium-potassium adenosine triphosphatase activity in gill were significantly affected by dietary n-3HUFA (p < 0.05), both of them showing a downward trend after upward. Malic dehydrogenase and superoxide dismutase activities in serum were also significantly affected by dietary n-3HUFA (p < 0.05), which rose first and then decreased in general, both of them have a maximum in 2.39% group. No significant differences of the activities of aspartate transaminase and alanine transaminase were observed among all groups (p > 0.05). With dietary n-3HUFA increase, both ∑HUFA and n-3HUFA contents gradually increased in hepatopancreas and tail muscles (p < 0.05). Based on broken-line regression analysis of WGR, the optimal n-3HUFA requirement is 0.89% for juvenile L. vannamei with initial weight of 0.50 ± 0.01 g. K E Y W O R D Santioxidant enzymes activities, fatty acid compositions, growth performance, Litopenaeus vannamei, n-3HUFA

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“…ALT and AST are two important indexes to reflect the liver function. Under normal conditions, the activity of transaminase in serum remained low, unless the tissues are damaged or lesions (Nazeri, Farhangi, & Modarres, 2017;Santhoshkumar et al, 2017). Studies in humans have shown that if the activity of transaminase does not exceed the normal value, even lower, the liver is considered to be in health state (Guh et al, 1995;Karmen, Wróblewski, & Ladue, 1955).…”

Section: Fat Composition (G/kg)mentioning

confidence: 99%

Effect of the dietary phosphatidylcholine at different growth stages of Pacific white shrimps,Litopenaeus vannamei

et al. 2019

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This study investigated the effects of dietary phosphatidylcholine (PC) at different growth stages of Litopenaeus vannamei (L. vannamei) with an initial weight of 0.70 ± 0.00 g (juvenile) and 4.25 ± 0.00 g (subadult) for 8 weeks. Six isonitrogenous and isoenergetic diets containing PC (0, 1.7, 5.1, 6.8, 10.2 and 13.6 g/kg) were confected using formulated with redfish meal, dehulled soybean meal and peanut meal as protein source, fish oil and corn oil as fat source. The juveniles were reared in 0.3 m3 aquarium at the density of 40 in triplicates, as well as the subadults in 0.5 m3 at the density of 40 in triplicates. Results showed PC level had significant effects on weight gain rate (WGR), specific growth rate, feed conversion ratio in juvenile and subadult shrimps and hepatosomatic index in juvenile shrimps (p < 0.05). No significant differences were found in moisture, whole body protein and crude ash (p > 0.05). Crude fat of juveniles had no significant change (p > 0.05), but subadults increased significantly (p < 0.05). Both juveniles and subadults showed that triglyceride and low‐density lipoprotein presented a downward trend with PC elevating, but high‐density lipoprotein increased gradually. Cholesterol in juveniles presented upward, but downward in subadults (p < 0.05). Dietary PC also significantly reduced the aspartate transaminase in juveniles and alanine transaminase in subadults (p < 0.05). PC supplementation significantly improved the glutathione S‐transferase activity and reduced the content of malondialdehyde in the hepatopancreas (p < 0.05). PC supplementation significantly improved gill filament sodium‐potassium adenosine triphosphatase enzyme of juvenile shrimps (p < 0.05), but subadult shrimps were not influenced (p > 0.05). PC supplementation significantly elevated the content of hepatopancreas eicosapentaenoic acid, highly unsaturated fatty acid (HUFA) and n‐3HUFA (p < 0.05), but the content of linoleic acid significantly reduced (p < 0.05). The broken‐line and quadratic regression model based on WGR showed the optimum dietary PC requirement was 10.3 g/kg and 6.5 g/kg for juveniles and subadults, respectively.

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The effect of different dietary inclusion levels of rutin (a flavonoid) on some liver enzyme activities and oxidative stress indices in rainbow trout,Oncorhynchus mykiss(Walbaum) exposed to Oxytetracycline

Cited by 38 publications

References 23 publications

Beneficial effects of thyme (Thymus vulgaris) extract on oxytetracycline-induced stress response, immunosuppression, oxidative stress and enzymatic changes in rainbow trout (Oncorhynchus mykiss)

Beneficial effects of thyme (Thymus vulgaris) extract on oxytetracycline-induced stress response, immunosuppression, oxidative stress and enzymatic changes in rainbow trout (Oncorhynchus mykiss)

Effects of dietary n-3HUFA on juvenile white shrimp, Litopenaeus vannamei: Growth, feed utilization, antioxidant enzymes activities and fatty acid compositions

Effect of the dietary phosphatidylcholine at different growth stages of Pacific white shrimps,Litopenaeus vannamei

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