The effect of different collagen modifications for titanium and titanium nitrite surfaces on functions of gingival fibroblasts

Abstract

Our results demonstrate a simple, yet effective, method for collagen coating on titanium implants to improve the long term integration and stability of dental implants.

Biofunctionalization of Microgroove Surfaces with Antibacterial Nanocoatings

“…Implant materials with an antimicrobial interface promote the growth and proliferation of cells and inhibit the adhesion and expansion of bacteria [22]. Cell adhesion and a cellbiomaterial interface are complicated processes associated with a number of factors [23,24] such as cell biological behaviors and material surface properties as well as environmental factors including hydrophilicity, charge, roughness, hardness, and chemical composition [25]. For example, material surface roughness affects cell spreading.…”

Expression of genes encoding IGFBPs, SNARK, CD36, and PECAM1 in the liver of mice treated with chromium disilicide and titanium nitride nanoparticles

“…Moreover, titanium dioxide nanoparticles synthesized as nanoneedles, titanate scrolled nanosheets, and gel-sol-based isotropic nanoparticle aff ect intracellular calcium homeostasis, thereby leading to endoplasmic reticulum stressdependent toxicity (Simon et al 2017). However, the genotoxicity of titanium nitride nanoparticles, which have favorable properties and are used for coronary stents, syringe needles, and the coating of orthopedic implant as well as in dental medicine for improving long-term implants (van Hove et al 2015;Chu et al 2016;Karjalainen and Nammas 2016;Ritz et al 2016), has not been studied yet. Very little is known about the toxicity of chromium containing nanoparticles (Alarifi et al 2016).…”

“…about the toxicity, including genotoxicity, induced by these nanoparticles (van Hove et al 2015;Chu et al 2016;Karjalainen and Nammas 2016;Ritz et al 2016). At the same time, for ultrafi ne titanium dioxide nanoparticles, which are widely used in the number of applications, including white pigment in paint, ceramics, food packaging materials, food additives, cosmetic creams, toothpastes, and components of surgical implants, it has been shown that the longterm exposure to titanium dioxide nanoparticles led to their accumulation in brain, oxidative stress, overproliferation of all glial cells, tissue necrosis as well as hippocampal cell apoptosis, which resulted in neurogenic disease states in mice (Ze et al 2014;Rollerova et al 2015).…”

Effect of chromium disilicide and titanium nitride nanoparticles on the expression of NAMPT, E2F8, FAS, TBX3, IL13RA2, and UPS7 genes in mouse liver

“…Furthermore, recently was shown that oral administration of titanium dioxide nanoparticles disrupts hepatic metabolic functions in a mouse model [3]. Titanium nitride nanoparticles have favorable proper ties and are used for the coating of orthopedic implant, coronary stents, and syringe needles as well as for improving long-term implants in dental medicine [4][5][6][7]. At the same time, very little is known about the toxicity including genotoxicity induced by titanium nitride nanoparticles and the effect of these nanoparticles on liver gene expressed profile has not been reported.…”

“…For titanium dioxide nanoparticles, which are widely used in the number of applications, including cosmetic creams, toothpastes, and component of surgical implants, it was shown that long-term exposure to these nanoparticles led to accumulation of these nanoparticles in brain, over-proliferation of glial cells and significant changes in brain gene expressions as well as to neurogenic disease states in mice [1,2]. At the same time, the genotoxicity of titanium nitride nanoparticles, which have favorable properties and used for coronary stents, syringe needles, and the coating of orthopedic implant as well as in dental medicine for improving long-term implants [4][5][6][7], did not studied yet. At the same time, very little is known about the toxicity of chromium containing nanoparticles [8].…”