The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the placenta for 2-series prostaglandins

Elmes, M; Tew, Priya; Cheng, Zhangrui; Kirkup, S E; Abayasekara, D R E; Calder, Philip C.; Hanson, Mark A.; Wathes, D C; Burdge, Graham C.

doi:10.1016/j.bbalip.2004.09.004

Cited by 37 publications

(30 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Thomas et al [6] hypothesised that fermentation conditions in the rumen were modified and that more propionate was available for the soybean oil cows and this explained the higher insulin levels observed. Saturated FA (18:0) did not modify the acetate/propionate ratio in in vitro rumen fermentation [12] and highly unsaturated FA (fish oil) are relatively resistant to fermentation in the rumen [33]. Therefore, in the present experiment insulin levels were not modified differentially by dietary treatment because 18:2n-6 and 18:3n-3 probably influenced the acetate/ propionate ratio to the same extent [12].…”

Section: Follicle Growth and Progesterone Concentrationsmentioning

confidence: 51%

“…In addition, it is known that unsaturated fatty acids (FA) are able to increase the concentrations of propionate produced in the rumen [12], which could increase both glucose production by the liver and insulin release from the pancreas. Rumen fermentation may be more strongly orientated towards propionate (insulin) production by a 18:3n-3 supplement compared to a 18:2n-6 supplement since 18:3n-3 is more unsaturated than 18:2n-6.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of a supplement rich in linolenic acid added to the diet of post partum dairy cows on ovarian follicle growth, and milk and plasma fatty acid compositions

et al. 2006

View full text Add to dashboard Cite

-The objective of this study was to determine the effect of a linseed supplement on follicle growth, progesterone concentrations and milk and plasma fatty acids in dairy cows post partum. Sixteen Holstein cows were given a basal total mixed diet plus one of two supplements: control (C; extruded soybeans; n = 8) or linseed (L; extruded linseeds; n = 8). One month after calving oestrous cycles were synchronised (PRID ® ). Follicle growth and milk progesterone concentrations were measured every 2 d over the induced oestrous cycle. Milk production characteristics were unaffected by treatment. The L cows lost significantly more BCS than the C cows (P < 0.01). Plasma insulin, glucose and urea were unaffected by the treatment. Plasma NEFA tended to be affected by the treatment (L > C, P = 0.08). The proportions of 18:3n-3 in milk and plasma were increased by L compared to C (P < 0.001 and P < 0.01, respectively). There was an effect of dietary supplement on the numbers of small follicles (L < C, P < 0.05). Milk progesterone was unaffected by treatment. In conclusion, the increased supply of 18:3n-3 to the cows had only a modest effect on follicle populations and corpus luteum activity was unchanged.linolenic acid / milk and plasma fatty acids / follicle growth / dairy cows

show abstract

Section: Follicle Growth and Progesterone Concentrationsmentioning

confidence: 51%

Section: Introductionmentioning

confidence: 99%

Effect of a supplement rich in linolenic acid added to the diet of post partum dairy cows on ovarian follicle growth, and milk and plasma fatty acid compositions

et al. 2006

View full text Add to dashboard Cite

show abstract

“…Elevated plasma concentrations of LA in the groups receiving vegetable oil (C, 3 week and 6 week) were associated with significantly higher AA concentrations, despite AA being absent from the vegetable oil. Elmes et al (2004) also fed maternal diets differing in LA (3 v. 0.16 g/ewe per day) and showed significantly increased concentrations of AA in ewe and lamb plasma at the end of gestation at the higher inclusion rate. In the present study, while the ewes show a graded increase in plasma concentrations of LA and AA with increased periods of receiving vegetable oil, this trend was not mirrored in the lambs.…”

Section: Discussionmentioning

confidence: 99%

Neonatal lamb vigour is improved by feeding docosahexaenoic acid in the form of algal biomass during late gestation

Pickard

Beard

Seal

et al. 2008

Animal

View full text Add to dashboard Cite

To determine whether feeding a sustainable, algal source of docosahexaenoic acid (DHA) to sheep during late pregnancy would improve neonatal lamb vigour, 48 English mule ewes, of known conception date, were divided into four treatment groups. For the last 9 weeks of gestation, ewes received one of two dietary supplements: either a DHA-rich algal biomass providing 12 g DHA/ewe per day, or a control supplement based on vegetable oil. The four dietary treatment groups (n 5 12) were: control supplement for the duration of the trial (C), DHA supplement from 9 to 6 weeks before parturition (3 week), DHA supplement from 9 to 3 weeks before parturition (6 week) and DHA supplement for the duration of the trial (9 week). Dietary supplements were fed alongside grass silage and commercial concentrate. There was a tendency for gestation length to be extended with increased duration of DHA supplementation (P 5 0.08). After parturition, the concentrations of eicosapentaenoic acid (EPA) and DHA in ewe and lamb plasma and colostrum were elevated in line with increased periods of DHA supplementation. Lambs from the 6-week and 9-week groups stood significantly sooner after birth than lambs from the C group (P , 0.05). These data show that neonatal vigour may be improved by the supplementation of maternal diets with DHA-rich algal biomass and that this beneficial effect depends upon the timing and/or duration of DHA allocation.

show abstract

“…Although the relative weight percentage of arachidonic acid was low in all cows, cows supplemented with high-linoleate safflower seeds had increased plasma concentrations of arachidonic acid over cows fed the control supplement. Increases in plasma arachidonic acid were also noted in ewes fed a diet high in linoleic acid [7]. Relative plasma concentrations of arachidonic acid were similar in oleic and linoleate supplemented cows possibly due to the amount of linoleic acid present in the high-oleic safflower seed supplement.…”

Section: Discussionmentioning

confidence: 86%

“…Supplementing cows with dietary lipid increased concentrations of serum lipids [1,2], altered ovarian follicular development [2,3], and prostaglandin (PG) synthesis [4][5][6]. In late-pregnant ewes, diets high in linoleic acid increased plasma concentrations of arachidonic acid [7] and production of PG from endometrial tissue [7,8].…”

Section: Introductionmentioning

confidence: 99%

Dietary supplementation with safflower seeds differing in fatty acid composition differentially influences serum concentrations of prostaglandin F metabolite in postpartum beef cows

et al. 2005

View full text Add to dashboard Cite

-Synthesis and secretion of prostaglandin F 2α (PGF 2α ) is elevated following parturition and exerts divergent effects on the re-establishment of fertile estrous cycles in cows. The objective of these experiments was to determine if oil seed supplements differing in fatty acid composition differentially influence serum concentrations of the specific PGF 2α metabolite, PGFM. Safflower seed supplements were formulated to provide 5% of dry-matter intake as fat. In Trial 1, 24 multiparous beef cows were individually fed control (beet pulp-soybean meal) or cracked high-linoleate safflower seed (78% 18:2n-6) supplements for 80 d postpartum. Linoleate supplemented cows had greater (P < 0.001) serum concentrations of PGFM than control cows. In Trial 2, primiparous beef cows (n = 36) were individually fed control (cracked corn-soybean meal), cracked high-linoleate (76% 18:2n-6) or -oleate (72% 18:1n-9) safflower seed supplements for 92 d postpartum. As in Trial 1, serum concentrations of PGFM were greater (P ≤ 0.04) in linoleate than control or oleate supplemented cows. Serum concentrations of PGFM, however, did not differ (P = 0.40) among oleate and control supplemented cows. Although potential impacts on reproductive performance remain to be proven, dietary oil supplements high in linoleate, but not oleate, increased serum concentrations of PGFM compared to control supplements. beef cows / lipid supplementation / prostaglandin

show abstract

The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the placenta for 2-series prostaglandins

Cited by 37 publications

References 41 publications

Effect of a supplement rich in linolenic acid added to the diet of post partum dairy cows on ovarian follicle growth, and milk and plasma fatty acid compositions

Effect of a supplement rich in linolenic acid added to the diet of post partum dairy cows on ovarian follicle growth, and milk and plasma fatty acid compositions

Neonatal lamb vigour is improved by feeding docosahexaenoic acid in the form of algal biomass during late gestation

Dietary supplementation with safflower seeds differing in fatty acid composition differentially influences serum concentrations of prostaglandin F metabolite in postpartum beef cows

Contact Info

Product

Resources

About