2022
DOI: 10.3389/fphar.2022.922015
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The effect of dietary fiber supplement on prevention of gestational diabetes mellitus in women with pre-pregnancy overweight/obesity: A randomized controlled trial

Abstract: Objective: To investigate the effect of dietary fiber intake during pregnancy on the prevention of gestational diabetes mellitus (GDM) in women who are overweight/obese prior to pregnancy.Methods: This randomized controlled trial was conducted in Shanghai General Hospital from June 2021 to March 2022. A total of 98 women who reported BMI≥24 kg/m2 prior to pregnancy were recruited before their 20th gestational week, and randomly (simple random allocation) assigned to the fiber supplement group (12 g of dietary … Show more

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Cited by 7 publications
(7 citation statements)
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References 54 publications
(57 reference statements)
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“…Two studies in the preconception period were identified. Among the eighty-four studies included, fifteen were conducted in United States [ 29 31 , 35 , 42 , 48 , 49 , 55 , 56 , 61 , 62 , 66 , 71 , 74 , 84 ], eight in China [ 24 , 25 , 67 , 73 , 93 , 95 , 96 , 99 ], eight in Italy [ 38 , 39 , 44 , 59 , 63 , 78 , 82 , 83 ], eight in Australia [ 36 , 47 , 57 , 58 , 72 , 75 , 80 , 107 ], seven in Iran [ 65 , 68 , 69 , 88 , 94 , 98 , 106 ], five in the United Kingdom [ 26 , 40 , 51 , 100 , 103 ], four in Finland [ 60 , 91 , 92 , 102 ], four in the Republic of Ireland [ 27 , 37 , 79 , 81 ], four in Denmark [ 33 , 43 , 46 , 77 ], three in Norway [ 54 , 85 , 86 ], two in each of India […”
Section: Resultsmentioning
confidence: 99%
See 3 more Smart Citations
“…Two studies in the preconception period were identified. Among the eighty-four studies included, fifteen were conducted in United States [ 29 31 , 35 , 42 , 48 , 49 , 55 , 56 , 61 , 62 , 66 , 71 , 74 , 84 ], eight in China [ 24 , 25 , 67 , 73 , 93 , 95 , 96 , 99 ], eight in Italy [ 38 , 39 , 44 , 59 , 63 , 78 , 82 , 83 ], eight in Australia [ 36 , 47 , 57 , 58 , 72 , 75 , 80 , 107 ], seven in Iran [ 65 , 68 , 69 , 88 , 94 , 98 , 106 ], five in the United Kingdom [ 26 , 40 , 51 , 100 , 103 ], four in Finland [ 60 , 91 , 92 , 102 ], four in the Republic of Ireland [ 27 , 37 , 79 , 81 ], four in Denmark [ 33 , 43 , 46 , 77 ], three in Norway [ 54 , 85 , 86 ], two in each of India […”
Section: Resultsmentioning
confidence: 99%
“…Nine studies based their intervention on the supplement inositol (myo-inositol, d-chiro-inositol or combination of both) [ 38 , 39 , 44 , 68 , 78 , 79 , 82 , 83 , 100 ] while four used probiotic supplementation (Lactobacillus and Bifidobacterium species) [ 36 , 60 , 77 , 98 ]. In three studies, the impact of vitamin D was assessed [ 52 , 94 , 101 ] and two evaluated the intake of soluble fibre [ 42 , 73 ] of which one study additionally provided women with frozen blueberries [ 42 ]. Metformin was used as a pharmacological intervention in eleven RCTs [ 40 , 41 , 47 , 50 , 85 90 , 108 ].…”
Section: Resultsmentioning
confidence: 99%
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“…It is triggered by higher weight gain, body mass index (BMI), advanced maternal age, conceiving age, and metabolic disorders [ 7 ]. Recurrent GDM during subsequent pregnancies is most strongly associated with a strong family history of T2DM and GDM [ 8 ].…”
Section: Introductionmentioning
confidence: 99%