Aims To identify the effect of Video Gaming on Heart rate variability, Autonomic Changes, Visual Evoked
Potential, Cognition, and the effect of long hours of video game playing This study is an Method
observational study conducted among the volunteered medical students studying at Sri Venkateshwaraa Medical College
Hospital and Research centre, Ariyur, Puducherry in the year from 2018 to 2021, who are playing video games, and the study
was conducted from January 2021-December-2021. The study subjects were interviewed individually, anthropometric
parameters, electrocardiogram, Heart Rate (HR), Blood Pressure (BP), Body Mass Index (BMI), Heart rate variability (HRV),
Visual Evoked Potential (VEP), Cognition test using Mini-mental status examination (MMSE) 27 were done and data were
collected, recorded, and analyzed. Out of 400 study population, males: females (183 (45.8%): Results 270 (54.2%) with a
median age of 20.605 ± 0.9702 based on video games played intermittently in 24 hours students were divided into 3 categories,
The 1st category played games for ≤ 3 hours (n= 223), 2nd category who played 4-6 hours (n=123), and students played > 6
hours were 54. 311 students played video games using mobile and 89 students used Laptops there was a statistical signicance
among the categories. Among 400 students playing games 145 students' BMI was ≥ 25 (0.00007) (Chi-square - 19.0763) , 47
students' heart rate was abnormal among them 33 showed Bradycardia 14 showed Tachycardic and there was statistical
signicance among the categories. 193 students' BP was low, 79 students' BP was high (<0.00001) (Chi-square - 48.0334), and
there was a statistical signicance among the categories Among the 400 student's Heart R (0.0314) (Chi-square –10.6033). ate
Variability results, <50 milliseconds (unhealthy value) of SDNN was found in 44 students and there was a statistical
signicance among the categories below and above the normal range of 53.5-82 milliseconds (0.00001)(Chi-square – 206.655),
(unhealthy value) of RMSSD for males was found in 59 students and below and above the normal range of 22-79 milliseconds
(unhealthy value) of RMSSD for females was found in 53 students there was a statistical signicance among the categories
(0.0422)(Chi-square – 13.053), <50 milliseconds (unhealthy value) of PNN-50 was found in 58 students and there was a
statistical signicance among the categories . Out of 400 Students >0.4 milliseconds (<0.00001)(Chi-square – 129.0331)
(unhealthy value) of Total Power was found in 115 students and there was a statistical signicance among the categories
(0.0471) (Chi-square – 6.1101), >0.4 milliseconds (unhealthy value) of Ratio of High and Low-Frequency Powers of heart rate
variability was found in 137 students and there was a statistical signicance among the categories (0.0176) (Chi-square –
8.0746). Among the 400 students' Visual Evoke Potential results, >100 milliseconds (unhealthy value) of were found in 118
students >100 milliseconds (unhealthy value) of N145 were found in 124 students, and there was a statistical signicance
among the categories , >100 milliseconds (unhealthy value) of P100 were found in 108 (0.00005) (Chi-square- 19.7573)
students, and there was a statistical signicance among the categories . Below and above (<0.00001) (Chi-square – 23.6437)
the normal range of 3.9-8.3microVolt (unhealthy value) of N75-P100 amplitude for the right eye was found in 48 males, below
and above the normal range of 5.9-12.3 microVolt (unhealthy value) of N75-P100 amplitude for the right eye was found in 49
female students there was a statistical signicance among the categories . Below and (<0.00001) (Chi-square – 121.8749)
above the normal range of 3.6-8.0microVolt (unhealthy value) of N75-P100 amplitude for the left eye was found in 34 males,
below and above the normal range of 5.1-11.5microVolt (unhealthy value) of N75-P100 amplitude for the left eye was found in 44
female students there was a statistical signicance among the categories . Among the 400 (<0.00001) (Chi-square – 93.632)
student's Mini-Mental Status Examinations (MMSE) for cognition results, the delayed response was given for all 5 sections of
MMSE by the students who played the games for > 6 hours. The results clearly explain that students Conclusions playing
games increases body weight, brings abnormality in heart rate, blood pressure, abnormal heart rate variability markers
showing decreased Autonomic Nervous System functions, abnormal visual evoke potential markers showing visual
impairment, and delayed responses in MMSE showing lesser cognitive capacities leading to poor quality of life, hence this
study will enlighten the knowledge of medical students (study population), and other medical students, psychiatrist, counselors
counseling kids, and youths who attempted suicide due to failure in video games, and other health care workers.
