The effect of COVID-19 disease diagnosed in the first trimester of pregnancy on obstetric outcomes

Abstract

Aim: The purpose of this article is to analyze the maternal, fetal, and obstetric outcomes of pregnancies diagnosed with coronavirus 2019 disease in the first trimester.
 Methods: A prospective analysis of patients diagnosed with COVID-19 during the first trimester of pregnancy and hospitalized was performed. Obstetric complications, delivery, and neonatal outcomes were reported in the following weeks of pregnancy.
 Results: We included seventy-five patients in the study. The mean age of pregnant women, Covid-19 positive, was 28.2 years, and the mean gestational week was 9.9 weeks. The mean delivery week was 31.65±9.47. Twenty-seven of the patients had preterm delivery. There was no neonatal Sars Cov-2 positivity among all the cases in any babies. Fifteen of twenty-nine patients with severe Covid-19 resulted in preterm delivery.
 Conclusion: Pregnant women with severe Covid-19 in their first trimester are at higher risk of premature birth, intrauterine fetal death, and perinatal complications