The Effect of Coronavirus Disease 2019 on Reproduction System and Fertility

Siregar, Muhammad Fidel Ganis; Siregar, Effinia Kamila Hanum

doi:10.3889/oamjms.2021.6346

Cited by 3 publications

(5 citation statements)

References 20 publications

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“…As a result, low level of hemoglobin will cause decrease of oxygen transport capability to peripheral tissues. Furthermore, there is an increased demand for oxygen during COVID-19 owing to the pneumonia (Siregar and Siregar, 2021;Soheili et al, 2022). Neutrophil to lymphocyte ratio is used as marker for inflammatory response that is better than single levels of neutrophils and lymphocytes count in assessing disease progression in some viral infections (Stanley et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

Overview of Covid-19 Cases in Pregnancy at the Hospital Universitas Sumatera Utara, Indonesia, When the Pandemic Storm Hit in the 2020-2022 Period.

Muhammad Ernesto Azguevara Ganis Siregar,

Salim Siregar,

Panusunan Lubis

et al. 2023

Afr. J. Infect. Dis.

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Background: COVID-19 (Coronavirus 2019) is caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome-Coronavirus-2), an acute infectious disease primarily affecting the respiratory system. Data on COVID-19 exposure during pregnancy and issues associated with COVID-19 during pregnancy remain limited. This research aimed to determine the number of pregnant women infected by COVID-19, laboratory test findings of pregnant women related to COVID-19 infection, infant outcome from mother with or without COVID-19 infection and referential status for COVID-19 and non-COVID-19 pregnant women at the USU Hospital during the 2020–2022 period. Materials and Methods: This research was conducted using a descriptive method with a cross-sectional study approach using a non-probability sampling technique by collecting secondary data from COVID-19 and non-COVID-19 pregnant women at the USU Hospital during the 2020-2022 period, where 112 samples were obtained. Results: The majority of COVID-19 pregnant women and non-COVID-19 pregnant women have been identified sequentially based on Hb (11.6%-decreased vs 79.5%-normal); Ht (11.6%-decreased vs 76.8%-increased); leukocytes (11.6%-increased vs 83%-normal); thrombocytes (8.9%-normal vs 86.6%-normal); PT (9.8%-normal vs 50.9%-normal); APTT (11.6%-normal vs 87.5%-normal); D-dimer (11.6%-long vs 56.3%-long); procalcitonin (7.1%-increased vs 87.5%-normal); NLR (8%-increased vs 82.1%-normal); CRP (12.5%-increased vs 87.5%-normal) and all of the baby outcomes were non-COVID-19 and the majority of pregnant women were not referred.Conclusion: Based on the data in this study, the majority of pregnant women and babies at the USU Hospital during the 2020–2022 period were non-COVID-19 positive and with non-referral status. Laboratory findings of COVID-19 in pregnancy significantly reveals abnormalities

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Section: Discussionmentioning

confidence: 99%

Overview of Covid-19 Cases in Pregnancy at the Hospital Universitas Sumatera Utara, Indonesia, When the Pandemic Storm Hit in the 2020-2022 Period.

Muhammad Ernesto Azguevara Ganis Siregar,

Salim Siregar,

Panusunan Lubis

et al. 2023

Afr. J. Infect. Dis.

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“…Reduced fertility can result not just from a loss in follicle quantity, but also from a decline in follicular quality. 8 There are a number of theories that have been established to explain the origins of aging-related changes.…”

Section: Discussionmentioning

confidence: 99%

“…Differences in serum TAC levels based on age, parity, BMI, and exercise status8 Whitney, b Kruskal-Wallis, aa Mann-Whitney (normoweight vs overweight), ab Mann-Whitney (normoweight vs obese), ac Mann-Whitney (overweight vs obese)…”

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confidence: 99%

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Differences of Serum Total Antioxidant Capacity Levels in Women with Early Menopause and Normal Menopause

Adhani,

Siregar,

Sukatendel

et al. 2023

Journal of South Asian Federation of Obstetrics and Gynaecology

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Introduction: Antioxidant can be defined as any substance that significantly delays and prevents the oxidation of an oxidizable substrate (oxidant). So that the causal relationship of menopause and the imbalance of oxidant-antioxidant becomes a reciprocal relationship and influences each other, decreases in antioxidant levels have been researched can cause oxidative stress, which triggers apoptosis in ovarian reserves. Objective: The purpose of this study is to compare the serum total antioxidant capacity (TAC) levels between early-menopausal and normalmenopausal women. Methods: This is an observational analytic study with a case-control design with 20 women with early menopause and normal menopause were included according to the inclusion and exclusion criteria by consecutive sampling, then the characteristic data were collected and grouped according to the study group. A blood test was done to assess serum TAC in the participants. Data were collected and processed, and statistical analysis was carried out. Results: It was found that there were differences in age at menopause in the group of participants who experienced early menopause and normal menopause. There were differences in TAC levels based on body mass index and TAC levels in early menopause and normal menopause. Conclusion: There are differences in serum TAC levels between early menopausal and normal menopausal women.

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“…A comprehensive review of existing literature indicates that while there is a significant body of research on the impact of pandemics on fertility/birth rates (Kirchengast & Hartmann, 2021;Aassve, et.al., 2021;Karasek, et.al., 2021;Pasternak, et.al., 2021;Molina, et.al., 2022), few studies have specifically focused on the direct relationship between global health crises and live birth rates in the Indonesian context. Most existing research incorporates a wide array of variables to explain fertility trends, including economic conditions, healthcare access, and environmental factors (Alfana, et.al., 2021;Siregar & Siregar, 2021;Akbar, et.al., 2022;Tjahyadi, et.al., 2022). This broad analytical scope, while valuable, often dilutes the direct impact of pandemics on fertility rates.…”

Section: Introductionmentioning

confidence: 99%

From Decline to Rebound: Analyzing the Dynamics of Fertility Trends in Sleman Regency Amid Global Shocks, 2018-2022

Alfana

2024

J Populasi

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This quantitative study aims to examine the trends of live birth rates in Sleman Regency over a five-year period (2018-2022). The study utilizes birth data obtained from the Ministry of Home Affairs (Kemendagri). The analysis focuses exclusively on live birth data without considering socio-economic indicators or environmental factors. The findings indicate that Sleman Regency experienced significant fluctuations in fertility trends amidst global challenges, including the Covid-19 pandemic. Initially, the fertility environment was stable, with a slight increase in live births from 13,102 in 2018 to 13,354 in 2019. However, a notable decline to 11,702 live births was observed in 2021, followed by a robust rebound to 14,908 live births in 2022. The study highlights the resilience of Sleman Regency’s demographic dynamics in the face of global disruptions. These findings underscore the importance of continuous monitoring and analysis of demographic data to anticipate and manage future demographic shifts. This research contributes to the demographic field by providing insights into the fluctuating fertility patterns in a specific region during a period marked by global disruptions.

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The Effect of Coronavirus Disease 2019 on Reproduction System and Fertility

Cited by 3 publications

References 20 publications

Overview of Covid-19 Cases in Pregnancy at the Hospital Universitas Sumatera Utara, Indonesia, When the Pandemic Storm Hit in the 2020-2022 Period.

Overview of Covid-19 Cases in Pregnancy at the Hospital Universitas Sumatera Utara, Indonesia, When the Pandemic Storm Hit in the 2020-2022 Period.

Differences of Serum Total Antioxidant Capacity Levels in Women with Early Menopause and Normal Menopause

From Decline to Rebound: Analyzing the Dynamics of Fertility Trends in Sleman Regency Amid Global Shocks, 2018-2022

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