“…histamine, (MIC S. aureus ¼ 0.125 mg mL; MIC S. epidermidis ¼ 0.125 mg mL À1 ), in the form of host-guest supramolecular complexes. 49,118 Comparison between antibacterial potency of 69 with those of its amine analogs 71-78, revealed that a rigid and basic structure of the C(3) arm is important for high antibacterial properties. 48,53 Derivatives, structurally similar to zwitterionic 71-78, obtained by Brucoli et al, were screened toward antibacterial potency against 69-resistant M. tuberculosis clinical isolates and "hypervirulent" HN-878 strains.…”