The Effect of Cognitive Functions on EEG in Patients with Juvenile Myoclonic Epilepsy

Abstract

SummaryObjectives: In this study, we aimed to show any effect of different types of cognitive activities on the electroencephalography (EEG) of patients with juvenile myoclonic epilepsy (JME).Methods: 30 patients with JME who stated that their seizures are not effected by any mental activity were submitted to a 30-minute standard awake video EEG. A neuropsychological activation battery (NPA) was performed during the ongoing video EEG. Results:The provocative effect of at least one test of NPA was observed in seven of 30 patients (23.3%) and the inhibitory effect of NPA was observed in nine of 30 patients (30.0%). Conclusion:We demonstrated that increased attention, concentration, and the tests associated generally with the frontal lobe functions were crucial for provocating the EEG discharges. This may support the studies with neuropsychological tests and structural neuroimaging techniques showing focal cortical abnormalities mainly associated with frontal lobe in JME.

The Effect of Cognitive Tasks During Electroencephalography Recording in Patients With Reflex Seizures

“…Due to the methodological differences, reported provocative rates of neuropsychological tasks vary widely from 18.6% to 84% in the studies including IGE and JME patients. [6][7][8][9][10][11][12] In the present study, 11.4% of our patients provoked by cognitive activation tasks, and all provoked patients were also in the IGE group. The activation rate is comparable to those reported by Maksuoka et al, 5 but much lower than the other cited literatures.…”

“…Only a few studies have been conducted to investigate the effect of cognitive functions on electroencephalographic (EEG) recordings, and reported provocative rates of neuropsychological tasks vary widely from 7.9% to 84% due to the methodological differences. [5][6][7][8][9][10][11][12] When the previous studies were evaluated, we concluded that the neuropsychological tests required a long amount of time range from 35 minutes to 6 hours, and the application of detailed neuropsychological tests during standard-awake EEG recording does not seem practical.…”

Analysis of the effects of different provocative methods on bioelectrical brain activity in patients with epilepsy

“…To kiam skir tu mui átakos ga lë jo tu rë ti tai, kad uþ sie nio au to riai nau do jo daugiau uþ duo èiø: pa pil do mai ty rë kal bë ji mo, skai ty mo ty liai ir gar siai, skai èia vi mo ty liai ir gar siai, ra ðy mo, erd vi nio màs ty mo po vei ká sme ge nø elek tro en ce fa li niam ak ty vumui, tai gi ir vi sø ðiø tes tø at li ki mas uþ tru ko il giau. Ta èiau ki to ty ri mo, at lik to su 30 pa cien tø im ti mi, re zul ta tai sutam pa su mû sø -30 % ti ria mø jø ste bë tas slo pi nan tis kogni ty vi nës sme ge nø veik los po vei kis EA [12]. Ly gi nant tiek anks èiau mi në to, tiek mû sø ty ri mo at ski rø tes tø at li kimo me tu gau tus duo me nis, sil pniau sias EP ak ty vuo jan tis po vei kis nu sta ty tas at lie kant skai ty mo gim tà ja kal ba uþduo tá.…”

“…Mû sø ty ri me EA kog ni ty vi niai tes tai ak ty vi no 11,46 % ti ria mø jø. Du ki ti ne di de liø im èiø (iki 30 ti ria møjø) ty ri mai pa tei kë di des nius kog ni ty vi niø uþ duo èiø ak tyva ci niam po vei kiui jaut riø pa cien tø skai èius -20 % [13], 23,3 % [12] ir 40-60 % (ver tin tas at ski rø uþ duo èiø pro voka ci nis po vei kis) [25], ta èiau H. Mat suo ka ir ben dra au toriai sa vo ty ri me nu ro dë pa na ðø á mû sø gau tus duo me nis pro cen tà -7,9 % (38 ið 480 tir tø jø). Be je, 36 ið 38 mi në to ty ri mo pa cien tø, ku riems kog ni ty vi nës uþ duo tys pa di di no EA, nuo vai kys tës sir go ge ne ra li zuo ta epi lep si ja [11].…”

“…Anks tes ni ty ri mai kog ni ty vi niø tes tø áta kà bio e lek tri niam sme ge nø ak ty vu mui ver ti no ser gan tiesiems spe ci fi në mis ge ne ti në mis ir re flek si në mis epi lep sijo mis, taip pat vai kams [6][7][8][9][10], o gau ti re zul ta tai -ne viena reikð miai. Su su au gu siais as me ni mis, ser gan èiais epilep si ja, at lik ta tik ke le tas to kiø ty ri mø [11][12][13], o di des nës im ties ty ri mø, kur ðie tes tai bû tø de ri na mi su stan dar ti niais pro vo ka ci niais te stais, ypaè Eu ro pos po pu lia ci jo je, mû sø þi nio mis, në ra. To dël mû sø dar bo tiks las bu vo áver tin ti stan dar ti niø pro vo ka ci niø më gi niø ir pa pil do mø kog ni tyvi niø uþ duo èiø po vei ká as me nø, ser gan èiø ge ne ra li zuo ta ir þi di ni ne epi lep si ja, bio e lek tri niam gal vos sme ge nø ak tyvu mui.…”