The effect of cognitive fatigue on prefrontal cortex correlates of neuromuscular fatigue in older women

Shortz, Ashley E.; Pickens, Adam; Zheng, Qi; Mehta, Ranjana K.

doi:10.1186/s12984-015-0108-3

Cited by 39 publications

(31 citation statements)

References 64 publications

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“…Previous studies demonstrated that some brain regions, such as the PFC, play an important role in regulating performance during cognitive-motor dual tasks. Reduction in PFC activity has been associated with reduced time to task failure during exercises with elevated cognitive demands (Mehta and Parasuraman, 2014 ; Shortz et al, 2015 ). This effect can be more pronounced in CRD patients as they need greater mobilization of brain resources to execute the same task.…”

Section: Performance Fatigability: Translation To Performance and Rehmentioning

confidence: 99%

Fatigue in Chronic Respiratory Diseases: Theoretical Framework and Implications For Real-Life Performance and Rehabilitation

Gruet

2018

Front. Physiol.

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Fatigue is a primary disabling symptom in chronic respiratory diseases (CRD) with major clinical implications. However, fatigue is not yet sufficiently explored and is still poorly understood in CRD, making this symptom underdiagnosed and undertreated in these populations. Fatigue is a dynamic phenomenon, particularly in such evolving diseases punctuated by acute events which can, alone or in combination, modulate the degree of fatigue experienced by the patients. This review supports a comprehensive inter-disciplinary approach of CRD-related fatigue and emphasizes the need to consider both its performance and perceived components. Most studies in CRD evaluated perceived fatigue as a trait characteristic using multidimensional scales, providing precious information about its prevalence and clinical impact. However, these scales are not adapted to understand the complex dynamics of fatigue in real-life settings and should be augmented with ecological assessment of fatigue. The state level of fatigue must also be considered during physical tasks as severe fatigue can emerge rapidly during exercise. CRD patients exhibit alterations in both peripheral and central nervous systems and these abnormalities can be exacerbated during exercise. Laboratory tests are necessary to provide mechanistic insights into how and why fatigue develops during exercise in CRD. A better knowledge of the neurophysiological mechanisms underlying perceived and performance fatigability and their influence on real-life performance will enable the development of new individualized countermeasures. This review aims first to shed light on the terminology of fatigue and then critically considers the contemporary models of fatigue and their relevance in the particular context of CRD. This article then briefly reports the prevalence and clinical consequences of fatigue in CRD and discusses the strengths and weaknesses of various fatigue scales. This review also provides several arguments to select the ideal test of performance fatigability in CRD and to translate the mechanistic laboratory findings into the clinical practice and real-world performance. Finally, this article discusses the dose-response relationship to training and the feasibility and validity of using the fatigue produced during exercise training sessions in CRD to optimize exercise training efficiency. Methodological concerns, examples of applications in selected diseases and avenues for future research are also provided.

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Section: Performance Fatigability: Translation To Performance and Rehmentioning

confidence: 99%

Fatigue in Chronic Respiratory Diseases: Theoretical Framework and Implications For Real-Life Performance and Rehabilitation

Gruet

2018

Front. Physiol.

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“…The main features of fNIRS, such as its portability and lower susceptibility to motion artifacts, allow researchers to measure changes in cortical activity during diverse motor tasks, ranging from moving the fingers and hands in clicking a mouse or keyboard during a Stroop task or computer game ( Carrieri et al, 2016 ; Harmat et al, 2015 ; Kashou et al, 2016 ; Shortz et al, 2015 ) to those body movements requiring coordination, such as juggling ( Carius et al, 2016 ) and balancing on a board ( Herold et al, 2017 ), and even to those requiring fine motor skills, such as simulating surgery ( Andreu-Perez et al, 2016 ) and flight ( Choe et al, 2016 ; Gateau et al, 2015 ). In addition, several recent studies have investigated the effects of bodily and road conditions, such as fatigue ( Xu et al, 2017 ), age ( Foy et al, 2016 ), and road curve ( Oka et al, 2015 ), on the hemodynamic responses of subjects during a driving simulation test.…”

Section: Applications Of Fnirs To Human Subjectsmentioning

confidence: 99%

Application of Functional Near-Infrared Spectroscopy to the Study of Brain Function in Humans and Animal Models

Kim

Seo

Jeon

et al. 2017

Molecules and Cells

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Functional near-infrared spectroscopy (fNIRS) is a noninvasive optical imaging technique that indirectly assesses neuronal activity by measuring changes in oxygenated and deoxygenated hemoglobin in tissues using near-infrared light. fNIRS has been used not only to investigate cortical activity in healthy human subjects and animals but also to reveal abnormalities in brain function in patients suffering from neurological and psychiatric disorders and in animals that exhibit disease conditions. Because of its safety, quietness, resistance to motion artifacts, and portability, fNIRS has become a tool to complement conventional imaging techniques in measuring hemodynamic responses while a subject performs diverse cognitive and behavioral tasks in test settings that are more ecologically relevant and involve social interaction. In this review, we introduce the basic principles of fNIRS and discuss the application of this technique in human and animal studies.

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“…Feelings of anxiety after a-SAH can highly restrict participation in daily activities [ 41 , 42 ]. Furthermore, PA can also be limited by concentration problems, [ 5 , 43 , 44 ] e.g. cycling activities are more demanding due to participation in traffic and multitasking.…”

Section: Discussionmentioning

confidence: 99%

Inactive lifestyles and sedentary behavior in persons with chronic aneurysmal subarachnoid hemorrhage: evidence from accelerometer-based activity monitoring

Harmsen

Ribbers

Heijenbrok‐Kal

et al. 2017

J NeuroEngineering Rehabil

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BackgroundAneurysmal subarachnoid hemorrhage (a-SAH) is a potential life-threatening stroke. Because survivors may be at increased risk for inactive and sedentary lifestyles, this study evaluates physical activity (PA) and sedentary behavior (SB) in the chronic phase after a-SAH.MethodsPA and SB were objectively measured at six months post a-SAH with an accelerometer-based activity monitor, with the aim to cover three consecutive weekdays. Total time spent in PA (comprising walking, cycling, running and non-cyclic movement) and SB (comprising sitting and lying) was determined. Also, in-depth analyses were performed to determine the accumulation and distribution of PA and SB throughout the day. Binary time series were created to determine the mean bout length and the fragmentation index. Measures of PA and SB in persons with a-SAH were compared to those in sex- and age-matched healthy controls.ResultsThe 51 participants comprised 33 persons with a-SAH and 18 controls. None of the participants had signs of paresis or spasticity. Persons with a-SAH spent 105 min/24 h being physically active, which was 35 min/24 h less than healthy controls (p = 0.005). For PA, compared with healthy controls, the mean bout length was shorter in those with a-SAH (12.0 vs. 13.5 s, p = 0.006) and the fragmentation index was higher (0.053 vs. 0.041, p < 0.001). Total sedentary time during waking hours showed no significant difference between groups (514 min vs. 474 min, p = 0.291). For SB, the mean bout length was longer in persons with a-SAH (122.3 vs. 80.5 s, p = 0.024), whereas there was no difference in fragmentation index between groups (0.0032 vs 0.0036, p = 0.396).ConclusionsPersons with a-SAH are less physically active, they break PA time into shorter periods, and SB periods last longer compared to healthy controls. Since inactive lifestyles and prolonged uninterrupted periods of SB are independent risk factors for poor cardiovascular health, interventions seem necessary and should target both PA and SB.Study registrationDutch registry number: NTR 2085.

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The effect of cognitive fatigue on prefrontal cortex correlates of neuromuscular fatigue in older women

Cited by 39 publications

References 64 publications

Fatigue in Chronic Respiratory Diseases: Theoretical Framework and Implications For Real-Life Performance and Rehabilitation

Fatigue in Chronic Respiratory Diseases: Theoretical Framework and Implications For Real-Life Performance and Rehabilitation

Application of Functional Near-Infrared Spectroscopy to the Study of Brain Function in Humans and Animal Models

Inactive lifestyles and sedentary behavior in persons with chronic aneurysmal subarachnoid hemorrhage: evidence from accelerometer-based activity monitoring

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