The effect of coenzyme Q10 on the exercise performance of cross-country skiers

Ylikoski, T.; Piirainen, Jarmo M.; Hänninen, Osmo; Penttinen, Jorma

doi:10.1016/s0098-2997(97)00038-1

Cited by 46 publications

(33 citation statements)

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“…Several randomised experimental studies on Q 10 supplementation and physical capacity have been undertaken (Braun et al, 1991;Snider et al, 1992;Porter et al, 1995;Laaksonen et al, 1995;Malm et al, 1997;Weston et al, 1997;Ylikoski et al, 1997). Out of 11 studies, ®ve indicated a positive effect of Q 10 on physical capacity, ®ve indicated no effect and one study a negative effect of Q 10 .…”

Section: Physical Capacitymentioning

confidence: 99%

Coenzyme Q10 in health and disease

et al. 1999

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Section: Physical Capacitymentioning

confidence: 99%

Coenzyme Q10 in health and disease

et al. 1999

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“…In this review we summarise the effects of CoQ 10 on skeletal muscle in terms of improving physical exercise capacity, in smooth muscle and endothelium in lowering blood pressure and in cardiac muscle in ameliorating cardiac failure. Wyss (1990) [1] C Untrained 18 +7% * +33% * Zeppili (1991) [2] C Trained & untrained 19 +11% ** +10% ** Amadio (1991) [3] C Athletes 10 +18% ** − Fiorella (1991) [4] C Athletes 22 − +13% * Bonetti (2000) [5] R Cyclists 28 0 +5% * Yilkoski (1997) [6] C Skiers 18 +3% * +5% ** C -Conference Report, R -Refereed Journal * P < 0.05; ** P < 0.01.…”

Section: Introductionmentioning

confidence: 99%

Systematic review of effect of coenzyme Q₁₀ in physical exercise, hypertension and heart failure

et al. 2003

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COENZYME Q10 IN PHYSICAL EXERCISE. We identified eleven studies in which CoQ10 was tested for an effect on exercise capacity, six showed a modest improvement in exercise capacity with CoQ10 supplementation but five showed no effect. CoQ10 IN HYPERTENSION. We identified eight published trials of CoQ10 in hypertension. Altogether in the eight studies the mean decrease in systolic blood pressure was 16 mm Hg and in diastolic blood pressure, 10 mm Hg. Being devoid of significant side effects CoQ10 may have a role as an adjunct or alternative to conventional agents in the treatment of hypertension. CoQ10 IN HEART FAILURE. We performed a randomised double blind placebo-controlled pilot trial of CoQ10 therapy in 35 patients with heart failure. Over 3 months, in the CoQ10 patients but not in the placebo patients there were significant improvements in symptom class and a trend towards improvements in exercise time. META-ANALYSIS OF RANDOMISED TRIALS OF COENZYME Q10 IN HEART FAILURE. In nine randomised trials of CoQ10 in heart failure published up to 2003 there were non-significant trends towards increased ejection fraction and reduced mortality. There were insufficient numbers of patients for meaningful results. To make more definitive conclusions regarding the effect of CoQ10 in cardiac failure we recommend a prospective, randomised trial with 200-300 patients per study group. Further trials of CoQ10 in physical exercise and in hypertension are recommended.

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“…The plasma level was not increased more, plateaued, while the dosage was increased from 2400 to 3000 mg/day of ubiquinol . The adequate plasma levels of CoQ10 may be important in inducing antifatigue effects according to the results from Mizuno's and Ylikoski's studies . We designed this dosage according to the results after supplementation of 300 mg/day of ubiquinone .…”

Section: Discussionmentioning

confidence: 99%

“…The adequate plasma levels of CoQ10 may be important in inducing One subject did not answer the questionnaire. BioFactors antifatigue effects according to the results from Mizuno's and Ylikoski's studies [17,39]. We designed this dosage according to the results after supplementation of 300 mg/day of ubiquinone [17].…”

Section: Tablementioning

confidence: 99%

Ubiquinol‐10 supplementation improves autonomic nervous function and cognitive function in chronic fatigue syndrome

et al. 2016

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The aim of this study was to evaluate the benefit of oral ubiquinol-10 supplementation in CFS patients using an open-label study and a randomized, double-blinded, placebo-controlled (RCT) study. Twenty patients with CFS were randomly enrolled in an 8-week open-label oral ubiquinol-10 (150 mg ubiquinol-10/day) study. The patients and the attending physicians were not blinded to the supplementation. Forty-three patients with CFS were randomly assigned to receive either ubiquinol-10 (150 mg/day) or placebo every day for 12 weeks. The patients and the attending physicians were blinded to the supplementation, and a total of 31 patients (N = 17 in the ubiquinol group and 14 in the placebo group) completed the study. The beneficial effects of ubiquinol-10 were observed in the open-label study we conducted prior to the RCT. The RCT results suggest that supplementation with ubiquinol-10 for 12 weeks is effective for improving several CFS symptoms. © 2016 BioFactors, 42(4):431-440, 2016.

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The effect of coenzyme Q10 on the exercise performance of cross-country skiers

Cited by 46 publications

References 1 publication

Coenzyme Q10 in health and disease

Coenzyme Q10 in health and disease

Systematic review of effect of coenzyme Q₁₀ in physical exercise, hypertension and heart failure

Ubiquinol‐10 supplementation improves autonomic nervous function and cognitive function in chronic fatigue syndrome

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The effect of coenzyme Q10 on the exercise performance of cross-country skiers

Cited by 46 publications

References 1 publication

Coenzyme Q10 in health and disease

Coenzyme Q10 in health and disease

Systematic review of effect of coenzyme Q10 in physical exercise, hypertension and heart failure

Ubiquinol‐10 supplementation improves autonomic nervous function and cognitive function in chronic fatigue syndrome

Contact Info

Product

Resources

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Systematic review of effect of coenzyme Q₁₀ in physical exercise, hypertension and heart failure