The Effect of Cocaine Upon the Eye.

Howe, Lucien

doi:10.1016/s0140-6736(02)28778-4

Cited by 3 publications

(2 citation statements)

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“…I think in one of these studies this notion was best summarized: 'withdrawal of many drugs is associated with a rebound increase in paradoxical sleep, both in terms of its duration and in terms of its intensity, the latter manifested by increased profusion of eye movements and greater intensity of the dreams' [105] . Therefore, it will be proved that none of the known [121] and yet unknown compounds will have the one and only one target on the cell membrane or its compartments as revealed earlier, e.g. for 9AA − aminoacridine [122] .…”

Section: Discussionmentioning

confidence: 91%

Addictive neurons

2018

Ther Targets Neurol Dis

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Since the reward center is considered to be the area tegmentalis ventralis of the hypothalamus, logically its neurons could mainly be responsible for addiction. However, the literature asserts that almost any neurons of CNS can respond to one or another addictive compound. Obviously not only addictive nicotine, but also alcohol, amphetamine, cannabis, cocaine, heroin and morphine may influence dopaminergic cells alone in VTA. Moreover, paradoxically some of these drugs ameliorate symptoms, counterbalance syndromes, cure diseases and improve health, not only those related to the CNS and in adults, but also almost all other organs and in children, e.g. epilepsy.

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Section: Discussionmentioning

confidence: 91%

Addictive neurons

2018

Ther Targets Neurol Dis

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“…8 In October and November of 1884, Koller’s work was already being discussed and expanded upon. 9,10 It is at this point that the first major distinction between the response of the United Kingdom and the United States becomes apparent.…”

Section: Local Anaesthesia: Cocaine’s Medical Miraclementioning

confidence: 99%

From gold-medal glory to prohibition: the early evolution of cocaine in the United Kingdom and the United States

Wielenga

Gilchrist

2013

JRSM Short Reports

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As reported in the 2011 World Drug Report, cocaine is likely to be the most problematic drug worldwide in terms of trafficking-related violence and second only to heroin in terms of negative health consequences and drug deaths. Over a period of 60 years, cocaine evolved from the celebrated panacea of the 1860s to outlawed street drug of the 1920s. As demonstrated by the evolution of cocaine use and abuse in the United Kingdom and United States during this time period, cultural attitudes influenced both the acceptance of cocaine into the medical field and the reaction to the harmful effects of cocaine. Our review of articles on cocaine use in the United Kingdom and the United States from 1860 to 1920 reveals an attitude of caution in the United Kingdom compared with an attitude of progressivism in the United States. When the trends in medical literature are viewed in the context of the development of drug regulations, our analysis provides insight into the relationship between cultural attitudes and drug policy, supporting the premise that it is cultural and social factors which shape drug policy, rather than drug regulations changing culture.

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Sherlock Holmes, Conan Doyle and cocaine

Dn¹

1994

Journal of the History of the Neurosciences

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The Effect of Cocaine Upon the Eye.

Cited by 3 publications

References 0 publications

Addictive neurons

Addictive neurons

From gold-medal glory to prohibition: the early evolution of cocaine in the United Kingdom and the United States

Sherlock Holmes, Conan Doyle and cocaine

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