The effect of chromium supplementation on apolipoproteins: A systematic review and meta-analysis of randomized clinical trials

Shahinfar, Hossein; Amini, Mohammad Reza; Sheikhhossein, Fatemeh; Djafari, Farhang; Jafari, Alireza; Shab‐Bidar, Sakineh

doi:10.1016/j.clnesp.2020.09.003

Cited by 2 publications

(2 citation statements)

References 38 publications

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“…CrPic 3 also assumes a protective role against dyslipidemia, since it improves the altered lipid profile [45], regulates triglycerides and HDL-c [54,55], and decreases serum cholesterol through the increase in SREBP, a transcription factor responsible for cellular cholesterol homeostasis [56]. However, it does not alter the levels of apolipoproteins ApoA and ApoB [57], markers of cardiovascular risk and metabolic syndrome [58]. Martin et al (2006) showed evidence that in patients with T2D, between 25-75 years old, CrPic 3 attenuated the increase in body weight, favored body fat distribution, and allowed for the decrease in glucose and increase in insulin sensitivity [47].…”

Section: Antidiabetic Effects Of Crpic 3 and Its Implications On Male...mentioning

confidence: 99%

A Comprehensive Review of the Impact of Chromium Picolinate on Testicular Steroidogenesis and Antioxidant Balance

et al. 2023

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Low testosterone (T) levels are a major cause of male infertility, as this hormone is crucial for several processes throughout the entire male reproductive tract. Leydig cells (LC) produce T through testicular steroidogenesis. Disrupted LC function can hinder steroid production and fertility. Among the factors that affect steroidogenesis, endocrine-disrupting chemicals (EDCs) raise concerns, as they disturb hormonal signaling. Chromium is classified as an EDC, and its main forms are hexavalent (Cr(VI)) and trivalent chromium (Cr(III)). While Cr(III) is controversially regarded as an essential metal, its compound Cr(III) picolinate (CrPic3) is used as a nutritional supplement due to its antidiabetic and antioxidant properties. This review aims to identify the possible effects of CrPic3 on testicular steroidogenesis and thus, on male fertility. The detriments caused by CrPic3 in LC include the inhibition of enzymes involved in steroidogenesis, and, as in other cells, the induction of mutagenesis and apoptosis. Remarkably, CrPic3 impacts male fertility through the alteration of reactive oxygen species (ROS), T levels, and sperm parameters (sperm motility and abnormal sperm count). However, gaps and inconsistencies exist in the literature concerning its effects on male fertility. Thus, further research is imperative to comprehend the underlying mechanisms of CrPic3 in the physiological processes relevant to male fertility, ensuring the supplement’s safety for use by men.

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Section: Antidiabetic Effects Of Crpic 3 and Its Implications On Male...mentioning

confidence: 99%

A Comprehensive Review of the Impact of Chromium Picolinate on Testicular Steroidogenesis and Antioxidant Balance

et al. 2023

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“…Hexavalent chromium is a highly toxic metal ion with non-biodegradable property and is perceived as the top priority on account for its higher toxicity, mutagenicity, and teratogenicity even at a very low concentration which makes hexavalent chromium impose high detrimental effects to human and the environment even at trace amount (He et al 2020). Hexavalent chromium can enter the human body in various ways and can accumulate easily in living organisms, causing severe illness such as respiratory lesions, skin allergies, malignancy, and even death in human beings (Shahinfar et al 2020). Therefore, the reduction or, if possible, suppression of the hexavalent chromium contamination in the environment is a critical urgent.…”

Section: Hexavalent Chromiummentioning

confidence: 99%

Simultaneous remediation of hexavalent chromium and organic pollutants in wastewater using period 4 transition metal oxide-based photocatalysts: a review

et al. 2021

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The contamination by hexavalent chromium and organic pollutants is a serious health issue. Moreover, hexavalent chromium can react with organic pollutants to form a complex which is difficult to treat, and thus remains in the natural environment for long times. Simultaneous photocatalysis can remove both organic pollutants and hexavalent chromium. Here we review the use of period 4 metal oxide-based photocatalysts for the removal of organic pollutants and hexavalent chromium. Titanium dioxide exhibited the highest performance, up to 100%, in removing both hexavalent chromium and organic pollutants from water. KeywordsTransition metal oxide • Period 4 • Simultaneous redox • Hexavalent chromium • Organic pollutants • Photocatalysis Abbreviations PAN/TiO 2 /Ag Modified polyacrylonitrile by silverdoped titanium dioxide TiO 2 /BiOCl Titanium dioxide supported by bismuth oxychloride A/R-TiO 2 Anatase/rutile titanium dioxide A/R-TiO 2 /BiOI Anatase-/rutile titanium dioxidesupported bismuth oxyiodide NM/TiO 2 Natural melanin-supported titanium dioxide Cr(VI)/MO Hexavalent chromium/methyl orange system * A. A. Jalil

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The effect of chromium supplementation on apolipoproteins: A systematic review and meta-analysis of randomized clinical trials

Cited by 2 publications

References 38 publications

A Comprehensive Review of the Impact of Chromium Picolinate on Testicular Steroidogenesis and Antioxidant Balance

A Comprehensive Review of the Impact of Chromium Picolinate on Testicular Steroidogenesis and Antioxidant Balance

Simultaneous remediation of hexavalent chromium and organic pollutants in wastewater using period 4 transition metal oxide-based photocatalysts: a review

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