The effect of chlorhexidine supplementation in a periodontal dressing

Abstract

Most commercial periodontal dressings claiming antibacterial activity lose this activity shortly after application. Chlorhexidine (CH) is an antibacterial agent with long-term activity in the oral cavity owing to its substantiveness and slow-release properties. In a double-blind split-mouth-designed clinical trial the effect of incorporating CH acetate in periodontal dressing was tested on wound healing after gingivectomy. Eleven patients, each needing at least two gingivectomies, constituted the test panel. Wound healing, as assessed by bleeding tendency after removal of dressing 7 days postoperatively was significantly delayed when control dressings were applied as compared with test dressings. Variables with regard to patient comfort also yielded results in favor of the test pack. Incorporation of antibacterial agents with high retention and slow release properties in the mouth in surgical dressings seems advantageous.

Time-dependent Decalcifying Effects of Endodontic Irrigants with Antibacterial Properties

“…CHX can bind phosphate, which in turn can lead to the release of small amounts of Ca 2ϩ from the root canal dentin. Provided that this assumption is true, CHX might show a possible indirect effect on the removal of Ca 2ϩ by binding the phosphate (30,31). In the present study, the least decalcifying effect (except water) was obtained with CHX between the two 5-minute intervals (5-to 10-minute and 10-to 15-minute).…”

Light-cured resin "Barricaid" - An aesthetic and biocompatible dressing: A step ahead

“…(1996),[5] Othman et al . (1989),[18] Asboe-Jorgensen et al . (1974)[19] who recorded higher bleeding scores following one week of periodontal surgery during the healing period.…”

Effects of topically applied agents on intra-oral wound healing in a rat model: a clinical and histomorphometric study*

“…chlorhexidine negatively affected fibroblast and keratinocyte proliferation in a concentration-and time-dependent manner (32)(33)(34)(35). However, only some in vivo studies (36, 37) indicated a negative effect of chlorhexidine on wound healing, while a considerable number of studies indicated the value of chlorhexidine rinses after various oral surgical procedures and a positive effect of chlorhexidine on wound healing (1,6,(38)(39)(40)(41)(42)(43)(44).…”