The effect of chlorhexidine gluconate irrigation on the root canal flora of freshly extracted necrotic teeth

Delany, Gael M.; Patterson, Samuel S; Miller, Chris H.; Newton, Carl W.

doi:10.1016/0030-4220(82)90469-8

Cited by 134 publications

(101 citation statements)

References 27 publications

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“…[2][3][4] Sodium hypochlorite (NaOCl) remains the most used irrigant due to its potent antimicrobial activity and lubricant and tissue-dissolving ability. 5 More recently, chlorhexidine has emerged as a potential irrigant, 6 given its broad-spectrum efficacy against oral bacteria. 7,8 In vivo and ex vivo studies comparing the antimicrobial effectiveness of chlorhexidine and NaOCl when used as irrigants during chemomechanical preparation have demonstrated conflicting results.…”

mentioning

confidence: 99%

Bacteriologic investigation of the effects of sodium hypochlorite and chlorhexidine during the endodontic treatment of teeth with apical periodontitis

Siqueira

Rôças

Paiva

et al. 2007

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, an

141

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Objective. This clinical study was undertaken to compare the effectiveness of 2.5% sodium hypochlorite (NaOCl) and 0.12% chlorhexidine digluconate as irrigants in reducing the cultivable bacterial populations in infected root canals of teeth with apical periodontitis. Study design. According to stringent inclusion/exclusion criteria, 32 teeth with primary intraradicular infections and chronic apical periodontitis were selected and followed in the study. Bacterial samples were taken at the baseline (S1) and after chemomechanical preparation using either NaOCl (n ϭ 16) or chlorhexidine (n ϭ 16) as irrigants (S2). Cultivable bacteria recovered from infected root canals at the 2 stages were counted. Isolates from S2 samples were identified by means of 16S rRNA gene sequencing analysis.

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mentioning

confidence: 99%

Bacteriologic investigation of the effects of sodium hypochlorite and chlorhexidine during the endodontic treatment of teeth with apical periodontitis

Siqueira

Rôças

Paiva

et al. 2007

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, an

141

View full text Add to dashboard Cite

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“…Chlorhexidine possesses adequate antimicrobial properties for an endodontic irrigant with 0.2% chlorhexidine, as shown by significant reduction in colony-forming units. 29,30 Sen et al 31 found chlorhexidine to be effective against C albicans. It has also been shown to be effective in eliminating bacteria penetrate up to 500 m within dentinal tubules.…”

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confidence: 99%

The antimicrobial effects of root canal irrigation and medication

Karim

Kennedy

Hussey

2007

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, an

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“…In the present study, all the tested solutions significantly reduced the microorganisms in oral cavity in a period of 3 minutes whereas 0.2% CHX didn't showed any reduction. CHX is a broad spectrum antimicrobial agent 11 , that can be used effectively as mouthwash, an irrigant [12][13][14][15][16][17] , disinfect the dentinal tubules [18][19][20] , and be absorbed into the dentin. Several researchers have pointed out the potential advantages of CHX as an antimicrobial medicament in endodontic therapy.…”

Section: Discussionmentioning

confidence: 99%

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2016

IJPSR

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ABSTRACT:To evaluate the antimicrobial activity of Octenidine (OCT) 0.1%, Chlorhexidine (CHX) 0.2% against bacterial strains of Enterococcus faecalis and Staphylococcus aureus. The strains were inoculated in 7ml of brain heart infusion broth and diluted to reach the concentration equivalent (0.5 McFarland standard). 1ml of organism suspension was contacted with 1ml of each mouthwash and was removed at time interval of 3,5 and 10 minute and plated on Brain Heart Infusion agar. After 72 hours of incubation, colony counts were measured using stereomicroscope. Kruskal Wallis test was conducted on mean number of CFU. Post-hoc tests were conducted by using the Mann Whitney U test and Duncan's-test of multiple comparisons. The results showed that OCT 0.1% was found to be the most effective in substantially reducing total bacterial counts after 3, 5 and 10 min time interval. OCT 0.1% was found to be the most effective in substantially reducing total bacterial counts.

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The effect of chlorhexidine gluconate irrigation on the root canal flora of freshly extracted necrotic teeth

Cited by 134 publications

References 27 publications

Bacteriologic investigation of the effects of sodium hypochlorite and chlorhexidine during the endodontic treatment of teeth with apical periodontitis

Bacteriologic investigation of the effects of sodium hypochlorite and chlorhexidine during the endodontic treatment of teeth with apical periodontitis

The antimicrobial effects of root canal irrigation and medication

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