1984
DOI: 10.14219/jada.archive.1984.0390
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The effect of chewing xylitol gum on the plaque and saliva levels of Streptococcus mutans

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Cited by 104 publications
(90 citation statements)
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“…The other is that the growth of P. gingivalis is inhibited when it is cultured with xylitol. The inhibitory effect of xylitol on the growth of mutans streptococci has been widely known (21,39,46). The mechanism of xylitol on impaired growth of mutans streptococci is suggested to be an intracellular accumulation of xylitol 5-phosphate, and this xylitol 5-phosphate inhibits the activity of bacterial glycolytic enzymes (43).…”
Section: Discussionmentioning
confidence: 99%
“…The other is that the growth of P. gingivalis is inhibited when it is cultured with xylitol. The inhibitory effect of xylitol on the growth of mutans streptococci has been widely known (21,39,46). The mechanism of xylitol on impaired growth of mutans streptococci is suggested to be an intracellular accumulation of xylitol 5-phosphate, and this xylitol 5-phosphate inhibits the activity of bacterial glycolytic enzymes (43).…”
Section: Discussionmentioning
confidence: 99%
“…In short-term habitual consumption, xylitol reduces the levels of MS assessed from both plaque and stimulated whole saliva [Loesche et al, 1984;Söderling et al, 1989]. Habitual long-term xylitol consumption appears to select for natural mutant cells of MS which are 'xylitol-resistant' [Trahan and Mouton, 1987].…”
mentioning
confidence: 99%
“…El vehículo más utilizado en varias investigaciones fue la goma de mascar 32,33,34 Loesche y col 16 ,encontraron que después del consumo de 5 mg de goma de mascar con xilitol por 4 semanas en niños con un promedio de edad de 8 años, los niveles de S. mutans en saliva y placa fueron reducidos en un 29.4% en comparación con los niveles basales y con el consumo de otros polioles. Además, la cantidad de placa también disminuyó y tuvo una mejor habilidad para resistir caídas en el pH inducidas por enjuagatorios con sacarosa.…”
Section: Discussionunclassified