The Effect of Chemotherapy on Serum Carnitine Levels and Fatigue in Chemotherapy Naive Medical Oncology Patients: A Pilot Study. Carnitine, Chemotherapy and Fatigue

Marx, Wolfgang; Teleni, Laisa; Ferguson, Maree; Walpole, Euan; Isenring, Elisabeth

doi:10.4172/2161-0509.1000131

Cited by 2 publications

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References 24 publications

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“…It includes under nutrition, which results from less food intake and hard physical work and over nutrition results from excess food intake and less physical activities [40].…”

Section: Malnutritionmentioning

confidence: 99%

Prevalence of Malnutrition and Associated Factors among Children Age 6-59 Months at Lalibela Town Administration, North WolloZone, Anrs, Northern Ethiopia

yalew¹

2013

J Nutr Disorders Ther

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Background: Children are most vulnerable to malnutrition in developing countries because of low dietary intakes, lack of appropriate care, and inequitable distribution of food within the household. Malnutrition remains one of the most common causes of morbidity and mortality among children throughout the world. Malnutrition In Ethiopia, in the form of stunting, underweight and wasting were identified as 44%, 29% and 10% and Amhara National region state 52%, 33.4% and 9.9%, respectively in children under five. The magnitude and various associated factors were not clearly known in the study area.Objective: To determine the prevalence of malnutrition and associated factors among Children age 6-59 Months in Lalibela Town, Northern Ethiopia. Methods:A-Community based cross-sectional study was conducted from August 19 to September 13, 2012 in Lalibela town, Northern Ethiopia which includes both urban and rural settings. Data were collected from 844 households with children age 6-59 months using pre tested structured questionnaires and measuring weight and height of children. Bivariate and multivariate logistic regression analyses were used using SPSS version 16 computer software to see the relevant associations. Anthropometric data were also converted into indices of nutritional status using Emergency Nutrition Assessment for SMART special software, 2012.Results: A total of 844 households were included in the study giving the response rate 100%. The prevalence of stunting, underweight and wasting were 47.3% (95%CI: 43.2-51.1), 25.6% (95%CI: 20.6-30.6) and 8.9% (95%CI: 6.9-10.2), respectively. Among the various socio-economic, demographic and child health and care practices characteristics considered, age of the child 11-23 months (AOR=2.30; (95%CI: 1.28-4.12), Deworming status (AOR=2.19); (95%CI: 1.41-3.39), sex of the child (AOR=0.75; (95%CI: 0.57-1.00) and breast feed the child still now (AOR=0.40; (95%CI: 0.20-0.78) remained to be significantly associated with stunting. Middle wealth quintile to the households (AOR=0.51; (95%CI: 0.28-0.91), age of the child 23-35 months (AOR=2.29; (95%CI: 1.14-4.61), number of children aged 6-59 months in the household (AOR=1.61); (95%CI: 1.08-2.41) and giving honey to the child in the morning (AOR=1.52; (95%CI: 1.03-2.24) were remained to be significantly and independently associated with underweight. Conclusion:The prevalence rate of malnutrition in the study area was found high and this was coupled with association of many independent variables. This needs appropriate factor specific interventions. five. Over two-thirds of these deaths, which are often associated with inappropriate feeding practices, occur during the first year of life [5]. Prevalence of Malnutrition and Associated Factors among ChildrenMalnutrition is one of the leading causes of morbidity and mortality in children under the age of five in developing countries [6]. Ethiopia being one of these countries malnutrition is an important public health problem; stunting, underweight and wasting were identified ...

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“…It includes under nutrition, which results from less food intake and hard physical work and over nutrition results from excess food intake and less physical activities [40].…”

Section: Malnutritionmentioning

confidence: 99%

Prevalence of Malnutrition and Associated Factors among Children Age 6-59 Months at Lalibela Town Administration, North WolloZone, Anrs, Northern Ethiopia

yalew¹

2013

J Nutr Disorders Ther

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Efficacy and Effectiveness of Carnitine Supplementation for Cancer-Related Fatigue: A Systematic Literature Review and Meta-Analysis

et al. 2017

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Background: Carnitine deficiency has been implicated as a potential pathway for cancer-related fatigue that could be treated with carnitine supplementation. The aim of this systematic literature review and meta-analysis was to evaluate the literature regarding the use of supplemental carnitine as a treatment for cancer-related fatigue. Methods: Using the PRISMA guidelines, an electronic search of the Cochrane Library, MEDLINE, Embase, CINAHL and reference lists was conducted. Data were extracted and independently assessed for quality using the Academy of Nutrition and Dietetics evidence analysis by two reviewers. In studies with positive quality ratings, a meta-analysis was performed using the random-effects model on Carnitine and cancer-related fatigue. Results: Twelve studies were included for review with eight reporting improvement in measures of fatigue, while four reported no benefit. However, many studies were non-randomized, open-label and/or used inappropriate dose or comparators. Meta-analysis was performed in three studies with sufficient data. Carnitine did not significantly reduce cancer-related fatigue with a standardized mean difference (SMD) of 0.06 points ((95% CI −0.09, 0.21); p = 0.45). Conclusion: Results from studies with lower risk of bias do not support the use of carnitine supplementation for cancer-related fatigue.

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The Effect of Chemotherapy on Serum Carnitine Levels and Fatigue in Chemotherapy Naive Medical Oncology Patients: A Pilot Study. Carnitine, Chemotherapy and Fatigue

Cited by 2 publications

References 24 publications

Prevalence of Malnutrition and Associated Factors among Children Age 6-59 Months at Lalibela Town Administration, North WolloZone, Anrs, Northern Ethiopia

Prevalence of Malnutrition and Associated Factors among Children Age 6-59 Months at Lalibela Town Administration, North WolloZone, Anrs, Northern Ethiopia

Efficacy and Effectiveness of Carnitine Supplementation for Cancer-Related Fatigue: A Systematic Literature Review and Meta-Analysis

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