The Effect of Castration and Peroral Estrogen Therapy on Some Psychological Functions

Estrogen Replacement Therapy In Older Women: A Neuropsychological And Brain MRI Study

“…Similar findings have also been described for older postmenopausal women after hormonal substitution 5,6 . In contrast, Rauramo and colleagues 7 failed to demonstrate any association between estrogen replacement therapy and neuropsychological performance, a finding that was later supported by a study of Barrett‐Connor and Kritz‐Silverstein 8 . A recent report provided new evidence for a possible benefit of estrogen substitution on cognitive functions as the authors described a decreased risk of Alzheimer's disease and improvement of cognitive deficits in women with this illness 9 …”

“…Memory loss is a frequent complaint of postmenopausal women 1–3 . Whether hormonal replacement therapy can alleviate such neuropsychological deficits remains controversial 4–9 . Sherwin et al 4 reported that oophorectomized women treated with estrogen scored better on four tests of cognitive function compared with a placebo group.…”

Enhanced Cognitive Performance with Estrogen Use in Nondemented Community‐Dwelling Older Women

“…By contrast, both Rauramo ct al. (1975) 34 and Barrett‐Connor and Kritz‐Silverstein (1993) 13 failed to demonstrate any association with test performance and any estrogen use.…”

Estrogen use among nursing home residents with a diagnosis of Parkinson's disease

“…[12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29] Of the two most recent double-blind estrogen trials on postmenopausal patients with Parkinson's disease (PD), one found a slight antiparkinsonian effect, 30 whereas the other found no benefit on motor function. [54][55][56][57][58][59][60][61] Three of the latest estrogen studies on cognition in PD show a lowered risk of developing dementia. [54][55][56][57][58][59][60][61] Three of the latest estrogen studies on cognition in PD show a lowered risk of developing dementia.…”