The effect of Camellia Sinensis (green tea) mouthwash on plaque-induced gingivitis: a single-blinded randomized controlled clinical trial

Abstract

Background and the purpose of the StudyComplementary medicine received high attention during last decades. We aimed to assess the efficacy of Green tea mouthwash on plaque-induced gingivitis as the most common form of periodontal disease.Methods and materialsWe designed a single blinded placebo controlled clinical trial. High school female students with chronic generalized plaque-induced gingivitis were distributed to receive either 5 ml of Green tea 5% two times/day or normal saline with the same dosage. Gingival index (Sillness & Loe), plaque index (Sillness & Loe) and bleeding index (Barnett) were recorded at baseline and five consecutive weeks. Comparisons were made by a general linear model, repeated measure ANOVA and a Bonferroni test applied for multiple comparisons.ResultsTwenty five students were recruited in each arm of the study. A significant improvement was observed in all periodontal indices during the study (P < 0.001). Two groups were contrasted by changing patterns of alteration of indices (P < 0.05). Although total amount of improvement was higher in mouthwash group, the differences did not reach a statistically significant level (P > 0.05, observed power for GI: 0.09, PI: 0.11 and BI: 0.07).ConclusionGreen tea mouthwash may be a safe and feasible adjunct treatment for inflammatory periodontal diseases. A future larger scale study is warranted for better evaluating the effect of green tea.

Effectiveness of green tea mouthwash in postoperative pain control following surgical removal of impacted third molars: double blind randomized clinical trial

“…Catechins of green tea (EGC, EGCg, and ECg) possess antibacterial activities and in vitro and in vivo studies have reported effectiveness of green tea against bacteria in periodontal diseases and caries [1,16]. Hence, the results of the current study could be also attributed to antibacterial properties of green tea mouthwash along with its anti-inflammatory activity.…”

“…Green tea is very rich in polyphenols including catechins which possess antioxidant, antidiabetic, antimutagenic, antiviral, antibacterial, and anti-inflammatory properties [15]. It has reported that green tea is effective on periodontal diseases and is also beneficial against cariogenic activities [16-19]. However, there exists no study to investigate benefits of green tea extract in controlling postoperative complications in oral surgeries.…”

Oxygen tension during biofilm growth influences the efficacy antimicrobial agents

“…Thus, it is thought that antioxidants may be beneficial in treating inflammatory diseases. Moreover, the systemic action of catechins seems to contribute to a decrease in the activity of proteinases 20 and a decrease in osteoclast formation 21 , thereby interfering with the normal course of periodontal diseases.…”

“…Our results corroborate evidence demonstrating in vitro antimicrobial activity of green tea on various bacteria 15,16 . Furthermore, the consumption of green tea can provide clinical benefits in the treatment of gingivitis 13,20 and periodontitis with greater reductions in probing depth and gains in clinical attachment 9 . It is possible that this systemic effect is due to the powerful antioxidant effects of green tea, as it is known that oxidative stress plays an important role in the pathogenesis of periodontal diseases.…”

Formulação à base de Epigalocatequina-3-galato, derivada do chá verde, desenvolvida para uso endodôntico: estudo físico-químico e biológico

“…Devido à sua comprovada eficácia contra os micro-organismos e na inibição de metaloproteinases, esse extrato tem sido incorporado em materiais odontológicos, tais como, adesivos dentinários (Du et al, 2012), resinas compostas Mankovskaia et al, 2013) e cimentos de ionômero de vidro (Hu et al, 2013). Além disso, seu uso tem sido sugerido na redução da erosão e abrasão dentária (Magalhães et al, 2009;Kato et al, 2010), em solução para bochechos (Hirasawa et al, 2006;Jenabian et al, 2012;Neturi et al, 2014;Sarin et al, 2015), em dentifrícios (Maruyama et al, 2011;Hrishi et al, 2015) e como meio para a conservação de dentes avulsionados após traumatismos, mantendo a vitalidade das células do ligamento periodontal (Hwang et al, 2011;Jung et al, 2011;Poi et al, 2013;Ghasempour et al, 2015).…”