The effect of cadmium on the digestive system of the teleost fish, Heteropneustes fossilis

Sastry, K.V.; Gupta, Priyanka

doi:10.1016/0013-9351(79)90050-1

Cited by 45 publications

(28 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, an increase in acid phosphatase activity was observed. This finding is in agreement with various studies carried out on heavy metal toxicity on freshwater fish in the liver and kidneys (Sastry and Subhadra, 1985;Sastry and Gupta, 1979). The rise in the activity of acid phosphatase due to lead toxicity suggests putative hepatocellular damage in the organism (Sharma, 1999).…”

Section: Discussion:-supporting

confidence: 92%

Toxicity Study of Lead Nitrate on Freshwater Fish Cirrhina Mrigala.

Fernandes¹

2016

IJAR

View full text Add to dashboard Cite

Chemicals present in the environment tend to alter the physiology of flora and fauna. Heavy metals tend to accumulate in the biosphere by virtue of their non-biodegradable nature. It is known that accumulation of heavy metals in tissues and organs results in cellular and molecular damage in various species (Cestari et al., 2004;Flora et al., 2012). The present study demonstrates the morphological and biochemical effects associated with the accumulation of the heavy metal lead in adult fish, Cirrhina mrigala (Common Indian Carp). Adults of Cirrhina mrigala were exposed to increasing concentrations of lead nitrate for a span of 96 hours, post which anatomical and biochemical changes were monitored. External morphology of adult fish and that of the liver and intestine were also qualitatively examined. The liver of treated fish appeared enlarged and had more mass compared with the control, whereas the intestine showed discolouration indicating ingestion of lead. Enzymes indicating stress and cellular damage were assayed in liver extracts prepared from exposed fish. The enzymes studied were succinate dehydrogenase, alanine transaminase, aspartate transaminase, acid phosphatase and alkaline phosphatase. A significant increase was foundin the activity of all of the enzymes except succinate dehydrogenase probably indicating hepatotoxicity. Succinate dehydrogenase activity was seen to have decreased, possibly indicating oxidative stress. Analysis of the neural marker enzyme acetylcholinesterase in brain extracts from these fish also showed a significant decrease in its activity which could lead to a misregulation in neurotransmission. These results directly reflect on the toxicity caused by accumulation of lead in the adult fish.Copy Right, IJAR, 2016,. All rights reserved.

show abstract

Section: Discussion:-supporting

confidence: 92%

Toxicity Study of Lead Nitrate on Freshwater Fish Cirrhina Mrigala.

Fernandes¹

2016

IJAR

View full text Add to dashboard Cite

show abstract

“…These results were in accordance with those of Durrieu & Tran-Minh when algae was exposed to Cd and Pb, finding an AP activity increase possibly due to phosphate ingestion by organisms. Sastry & Gupta (1979) point out the importance of studies on the pathological histology and biochemistry of aquatic organisms, which may show relevant effects as a result of toxicity elicited by metals such as Cd. These authors conducted histopathological studies of the liver and digestive tract of the teleost Heteropneustres fossilis treated with 6.8 mg/L of CdCl2, observing damage to connective tissue of the digestive tract, vacuolation of cytoplasm in hepatocytes, and rupture of the cell membrane leading eventually to hepatocyte degeneration and mitochondrial damage.…”

Section: Discussionmentioning

confidence: 99%

Biochemical and Mitochondrial Changes Induced by Cd, Fe and Zn in Limnodrillus hoffmeisteri

Ortega¹,

Ordoñez²,

Favari

et al. 2011

Int. J. Morphol.

View full text Add to dashboard Cite

SUMMARY:The effects of sublethal concentrations of cadmium (0.64 µg/L), iron (0.043 mg/L) and zinc (0.31 mg/L) and a mixture of these metals on succinate dehydrogenase (SD) and alkaline phosphatase (AP) activity and on structural changes in the mitochondria of epithelium cells of the digestive tract were examined in the oligochaete Limnodrillus hoffmeisteri after 96 h of exposure in artificial sediments. SD activity was significantly inhibited, particularly in treatments with Cd alone (92.57%), while AP increased its activity with Cd alone (73.23%). However, when this metal was mixed with Fe and Zn, the inhibition of SD activity was lower (67.82%) than with Cd alone, showing an antagonistic effect and AP increased its activity (73.26%). Mitochondria were structurally damaged by exposure to Cd alone. However, in the metal mixtures, the toxic effects may exert interactive effects eliciting a less structural damage in the mitochondria of epithelium cells of the digestive tract than when Cd is alone.

show abstract

“…Sastry and Gupta (1979) have reported vacuolation. degeneration of nuclei, accumulation of liptd and focal necrosis in liver cells of Heteropneustes fossilts subjected to sublethal concentration of cadmium chloride.…”

Section: A-collection Offish Samplesmentioning

confidence: 99%