The effect of AZD9567 vs. prednisolone on glycaemic control in patients with type 2 diabetes mellitus: Results from a phase 2a clinical trial
Philip Ambery,
Grzegorz Zajac,
Joachim Almquist
et al.
Abstract:AimsCorticosteroids are the treatment of choice for many inflammatory diseases but often lead to adverse effects, including hyperglycaemia. This study investigated the mechanisms driving differential effects on glucose control for AZD9567, an oral nonsteroidal selective glucocorticoid receptor modulator vs. prednisolone in 46 patients with type 2 diabetes mellitus.MethodsIn this randomized, double‐blind, 2‐way cross‐over study (NCT04556760), participants received either AZD9567 72 mg and prednisolone 40 mg dai… Show more
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