The Effect of Aster glehni Fr. Schm. Extracts on Whitening and Anti-Wrinkle

Abstract

Plants and their extracts can be utilized as inexpensive and rich resources of active constituents in the cosmetic field, as well as the food, pharmaceutical and medicinal fields. Until now, Aster glehni Fr. Schm. had no known active effect, except on anti-oxidation, that was found during investigations for application in the cosmetic field. In this study, we examined the inhibition of enzymatic reactions to protein levels in inclusive B16F10 melanoma cell lines. Significant inhibition of enzymatic reactions was observed in the EtOAc extract, which advanced to tyrosinase protein and TRP-1 in the B16F10 melanoma cell line. These results indicated that the effect of EtOAc extract inhibited expressions of tyrosinase protein and TRP-1 in the B16F10 melanoma cell line by 30.5% and 41.5% at 100ug/ml respectively. On the other hand, antimicrobial activity was evaluated to the four fractions in normal flora of the skin. Hexane extract was only exhibited in the higher clear zone in all strains. In con-

Aster glehni Extract Containing Caffeoylquinic Compounds Protects Human Keratinocytes through the TRPV4‐PPARδ‐AMPK Pathway

“…Other functions of AG have been reported previously as follows. An ethyl acetate extract of AG inhibited the protein expression of tyrosinase and tyrosinase-related protein 1, which are involved in melanin biosynthesis in melanocytes [11]. In another study, the ethyl acetate extract of AG showed antioxidant effect and inhibited the protein expression of induced nitric oxide synthase (iNOS), which is involved in inflammation [12].…”