The Effect of Argon Gas Pressure on Ice Ball Size and Rate of Formation

Sprenkle, Preston; Mirabile, Gabriella; Hruby, Gregory W.; Phillips, Courtney K.; Xavier, Keith; Gupta, Mantu; Landman, Jaime

doi:10.1016/s0022-5347(08)60703-x

Cited by 2 publications

(1 citation statement)

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“…Multiple studies have proved that temperature below −40 ℃ should be achieved to induce cryogenic destruction and complete cell death (21). Cryoablation is based on the Joule-Thomson effect, which means higher initial gas pressure is related with lower ablation temperature and formation of larger ice balls (22). Several cycles of freezing and thawing can lead to protein denaturation, cell membrane disruption and cell rupture due to osmotic shifts, and tissue ischemia due to microvascular thrombosis.…”

Section: Cryoablationmentioning

confidence: 99%

Image guided thermal ablation in lung cancer treatment

2020

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Lung ablation has been introduced into lung cancer treatment for about two decades. Currently, 3 main choices of thermal energy for lung ablation are radiofrequency ablation (RFA), microwave ablation (MWA), and cryoablation. As a mostly palliative, occasionally curative intent local treatment, the feasibility and safety of lung ablation have been validated in small size lung cancer treatment, especially in lung tumor ≤3 cm. Improved techniques and experience in recent years help render outcomes much better than before for lung cancer patients who are medically inoperable with early stage primary lung cancer, and patients with oligometastasis or local recurrence. For stage IA non-small cell lung cancer (NSCLC) patients underwent RFA, 1-and 2-year overall survival rate were reported as 86.3% and 69.8%. And 1and 2-year local recurrence rate were reported as 68.9% and 59.8%. Limitations, including heat sink, skin burn, and inconsistent heat conduction, are observed in the first applied ablation technique, RFA. MWA and cryoablation are developed to overcome these limitations and achieve the goal of less morbidity. Generally, imaged guided thermal ablation has a good safety profile, with pneumothorax as the most common morbidity. This article will mainly discuss the current features and application of these ablation techniques in lung cancer treatment.

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Section: Cryoablationmentioning

confidence: 99%

Image guided thermal ablation in lung cancer treatment

2020

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Tratamiento actual de las masas renales pequeñas

Soldevilla

Illa

Viscasillas

et al. 2009

Actas Urológicas Españolas

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In the event of elderly patients, concomitant diseases advising against surgery, multiple renal tumors, a solitary kidney, or patients who reject surgery, ablation procedures may be safe and effective when performed by expert hands, achieving mid-term oncological results similar to partial nephrectomy. Active surveillance has also been shown to be safe in the mid-term in adequately informed patients. To improve indications, new diagnostic procedures that help us differentiate the potentially more aggressive tumors will be required. Larger series and longer follow-ups are neede to confirm current results.

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The Effect of Argon Gas Pressure on Ice Ball Size and Rate of Formation

Cited by 2 publications

References 0 publications

Image guided thermal ablation in lung cancer treatment

Image guided thermal ablation in lung cancer treatment

Tratamiento actual de las masas renales pequeñas

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