The effect of antibiotics on the efficacy of oral contraceptives. A controversy revisited

Antibiotic and Oral Contraceptive Drug Interactions: Is There a Need for Concern?

“…Reports of oral contraceptive failure seem to be most numerous in women using preparations containing 30 m g of ethinylestradiol and 150 m g of levonorgestrel (27). Oral contraceptive drug interactions are thought by some to be more significant in women taking low dose preparations, although much controversy exists (28). Thus, one potential solution may be to increase the amount of ethinylestradiol in the preparation.…”

Advice given to women who are prescribed antibiotics while taking the oral contraceptive pill

“…6,8 However, such measures do not absolve the prescriber of the need to discuss potential drug side effects and interactions with his or her patients. Some authors have recommended that oral antibiotics should not be prescribed at all to patients who are taking the OCP; 10 other authors strongly disagree and feel that antibiotics can be prescribed to patients taking the OCP as long as the patient clearly understands the increased chances of pregnancy 11 and additional precautions are taken as appropriate. In the current study, the favoured method was that of educating the involved medical staff with additional emphasis that any advice claimed to have been given to a patient could not be substantiated in a court of law without an appropriate entry in the patient's medical notes.…”

Λειτουργική Μορφολογία Του Δέρματος Κατά Την Εμφάνιση Εξανθημάτων Φαρμακευτικής Αιτιολογίας

“…Παραδείγματα αποτελούν η αναστολή της απορρόφησης της γκριζεοφουλβίνης από την φαινοβαρβιτόνη, η αναστολή της απορρόφησης των τετρακυκλινών από τα αντιόξινα ενώ η απορρόφηση των αντισυλληπτικών μπορεί να μειωθεί κατά την σύγχρονη χορήγηση με τετρακυκλίνες (66) . Το τελευταίο, εντούτοις, αποτελεί αντικείμενο διαφωνίας (67) .…”