The effect of anti-müllerian hormone and progesterone concentrations on superovulation response and embryo yield in goats

In Vivo Embryo Production in Sheep and Goats

“…These are the management of donor and recipient animals, estrus synchronization of donor and recipient, donors' superovulation response, fertilization rate, embryo collection and evaluation, embryo transfer technique, and other factors affecting the survival of transferred embryos (Ishwar and Memon 1996). However, the most important factor affecting the success of embryo transfer, especially in sheep and goats, is the superovulation response that varies individual to individual (Cognie et al 2003;Lehloenya 2008;Karakas Alkan et al 2020;Karakas Alkan 2021). Superovulation response and number of transferable embryos considerably limit in vivo embryo production in cattle, sheep and goats (Cognie et al 2003;Sevgi et al 2019).…”

“…Individual differences are observed even in animals housed in the same group and undergoing the same superovulation protocol in in vivo embryo production. For this reason, it is very important to select animals that can respond better to superovulation treatments in recent years (Rico et al 2009;Monniaux et al 2010;Soquilla and Mingala 2017;Karakas Alkan et al 2020). Studies during the past decade have focused on the role of anti-Müllerian hormone (AMH) in predicting animal responses to gonadotropin treatments (La Marca and Volpe 2006;Monniaux et al 2010;Monniaux et al 2013;Sevgi et al 2019;Karakas Alkan et al 2020).…”

“…For this reason, it is very important to select animals that can respond better to superovulation treatments in recent years (Rico et al 2009;Monniaux et al 2010;Soquilla and Mingala 2017;Karakas Alkan et al 2020). Studies during the past decade have focused on the role of anti-Müllerian hormone (AMH) in predicting animal responses to gonadotropin treatments (La Marca and Volpe 2006;Monniaux et al 2010;Monniaux et al 2013;Sevgi et al 2019;Karakas Alkan et al 2020). In different animal species, higher AMH concentrations were associated with a better performance in terms of superovulation response and a higher potential for embryo production (Monniaux et al 2011).…”

“…AMH is known to be the best endocrine biomarker to predict follicle number and superovulation response in assisted reproductive technologies (La Marca and Volpe 2006). Since this hormone is expressed in granulosa cells of developing follicles and the highest AMH concentrations are found in antral follicles, AMH concentration measurement can be used to determine the follicle pool of donor animals (Monniaux et al 2013;Karakas Alkan et al 2020). Some researchers have reported a positive correlation between the number of small antral follicles and serum AMH concentrations (Gruijters et al 2003;Monniaux et al 2013;Abdel Aziz et al 2017).…”

“…In addition, superovulation response was measured to be higher in donors whose AMH concentration was high on the day of synchronization. Cut-off value in ROC curve analysis performed for the selection of donors with highest superovulation was determined to be 4.77 ng/ml (Karakas Alkan et al 2020). Lahoz et al (2014) reported that the determination of the plasma AMH concentration in a single blood sample before FSH treatment is a suitable method for selecting the best oocyte donors for embryo biotechnologies in prepubertal sheep.…”