The Effect of Anti-Allergic Herbal Formulation on the Quality of Life of Allergic Rhinitis Patients at the Tawangmangu Hortus Medicus Clinic

Abstract

Allergies are health problems that can affect a person’s quality of life. It is currently unknown whether the use of anti-allergic herbs can improve the quality of life for allergic patients. The purpose of this study was to determine the effect of giving anti-allergic herbs on the quality of life of patients with allergic rhinitis at the Tawangmangu Hortus Medicus Clinic. The design of this research was a pre-post treatment quasi experimental. A total of 55 subjects were given anti-allergic herbal decoction consisting of sembung, javanese chilies, ginger, and nut grass for 4 weeks and drunk 3 times a day. Before the study and on day 28th, the subjects were examined for quality of life using the Short Form-36. The results were analyzed using the Wilcoxon test. The results showed that there was a significant increase in quality of life between before and after drinking anti-allergic herbal medicine (p<0.05), especially for the dimensions of physical function, energy and general health. The conclusion is that anti-allergic herbs can improve the quality of life for allergic rhinitis patients.

Skrining Inhibitor Antihistamin Secara In Silico dari Senyawa Melati Belanda (Quisqualis indica L.)

“…Alergi merupakan salah satu reaksi hipersensitivitas imunologis akibat induksi IgE secara spesifik terhadap alergen yang berikatan dengan sel mast (Novianto et al, 2021) . Respon antigen pada suatu individu setelah mengalami sensitisasi dengan alergen tertentu disebut hipersensitivitas.…”

“…Reaksi hipersensitivitas tipe IV dipengaruhi oleh sel. Sel T CD4+ dan CD8+ berperan dalam reaksi tipe IV (Novianto et al, 2021). Prevalensi hipersensitivitas yang diperantai oleh IgE seperti asma, rinokonjungtivitis, eksema dan anafilaksis berdasarkan data WHO pada tabun 2003 diperkirakan terjadi >20% populasi di dunia.…”