The effect of anthelmintic resistance on the productivity in feedlot cattle

Fazzio, Luis Emilio; Sánchez, Ricardo Ortíz; Streitenberger, Nicolás; Galván, Walter Rubén; Giudici, Claudio; Gimeno, Eduardo Juan

doi:10.1016/j.vetpar.2014.10.010

Cited by 30 publications

(10 citation statements)

References 30 publications

(42 reference statements)

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“…The large-scale use of synthetic anthelmintics has reduced the efficacy of these drugs by driving the development of resistant parasites (Fazzio et al ., 2014; Gasbarre, 2014). Thus, the development of complementary methods for the control of bovine gastrointestinal parasitic nematodes is essential.…”

Section: Introductionmentioning

confidence: 99%

Arthrobotrys cladodes and Pochonia chlamydosporia in the biological control of nematodiosis in extensive bovine production system

Vieira¹,

Oliveira²,

Freitas³

et al. 2020

Parasitology

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Cattle production in extensive systems favours the occurrence of gastrointestinal nematodes, and the use of nematophagous fungi complements the control strategies for these nematodes. The aim of this study was to evaluate the effectiveness of the fungi Arthrobotrys cladodes and Pochonia chlamydosporia in the biological control of gastrointestinal parasitic nematodes in grazing cattle. Twenty-four calves were randomly divided into four groups and allocated to independent paddocks from February 2018 to January 2019. In the first group, the animals received pellets containing P. chlamydosporia. In the second group, the animals received pellets containing A. cladodes. In the third group, the animals received pellets containing a combination of the fungi A. cladodes and P. chlamydosporia. In the control group, the animals received pellets without fungus. The combined use of A. cladodes and P. chlamydosporia showed greater efficacy in the biological control of bovine gastrointestinal parasitic nematodes than the same fungi used separately. The parasite load was lower and weight gain was greater (P ⩽ 0.05) in the groups of cattle treated with nematophagous fungi. Therefore, the use of A. cladodes and P. chlamydosporia is promising in the biological control of nematodiosis in cattle.

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Section: Introductionmentioning

confidence: 99%

Arthrobotrys cladodes and Pochonia chlamydosporia in the biological control of nematodiosis in extensive bovine production system

Vieira¹,

Oliveira²,

Freitas³

et al. 2020

Parasitology

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“…Anti-helminthic drugs represent the main form used for the control of helminths; however, the results in the reduction in the parasitic load of the animals are not always satisfactory and these drugs can leave residues in products for human consumption. The reports of the development of anthelmintic resistance are very frequent and thus, it is necessary to search for complementary methods in the control of helminths (Fazzio et al ., 2014; Gasbarre, 2014).…”

Section: Introductionmentioning

confidence: 99%

Association and predatory capacity of fungi Pochonia chlamydosporia and Arthrobotrys cladodes in the biological control of parasitic helminths of bovines

et al. 2019

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Nematophagous fungi are used in the biological control of the parasitic helminths of animals and plants. The association of ovicidal and predator nematophagous fungi may present a complementary and increased action on the biological control of helminths. Joint growth compatibility and predation tests were carried out on infective larvae of nematode parasites of bovines with the nematophagous fungus ovicide Pochonia chlamydosporia and the nematophagous fungus predator Arthrobotrys cladodes. The tests of antagonism in direct confrontation, antibiosis and the effect of volatile metabolites between the isolates of P. chlamydosporia and A. cladodes indicated the viability of joint growth of these fungi. The association of the fungi P. chlamydosporia and A. cladodes presented a higher predatory capacity of infective larvae of the parasitic nematodes of bovines when compared to the predation of the fungi used alone. Therefore, under laboratory conditions, the fungi studied presented growth compatibility and the association of these increased the nematicidal activity against parasitic helminths of cattle.

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“…Resistance of Cooperia spp. to MLs is not rare; however, treatment failure is often not perceived by farmers because of the low pathogenicity of some species of Cooperia (except, for example, C. oncophora and C. punctata ) ( Cezar et al., 2010b , Fazzio et al., 2014 , Zanetti Lopes et al., 2014 ). Nevertheless, massive infections by Cooperia spp.…”

Section: Discussionmentioning

confidence: 99%

Anthelmintic resistance in gastrointestinal nematodes of beef cattle in the state of Rio Grande do Sul, Brazil

Ramos

Portella

Rodrigues

et al. 2016

International Journal for Parasitology: Drugs and Drug Resistan

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Gastrointestinal nematodes resistant to anthelmintics have been reported in several regions of Brazil, and they may be associated with economic losses for the cattle industry. This study aimed to evaluate the resistance status of gastrointestinal nematodes from naturally infected beef cattle to several commercially available anthelmintics, as well as to test the efficacy of combinations of anthelmintics against multi-resistant gastrointestinal nematodes. Ten farms located in Rio Grande do Sul state were selected by: farmers' consent; extensive raising system; availability of calves aged from 7 to 9 months naturally infected by gastrointestinal nematodes; absence of anthelmintic treatment for 60 days before the study; and presence of 70–100 calves or more of both genders with ≥200 eggs per gram of feces (EPG) (sensitivity of 50 EPG). These calves were distributed into 10 groups (of 7–10 animals) per farm and treated with ivermectin, doramectin, eprinomectin, fenbendazole, closantel, nitroxynil, disophenol, levamisole, albendazole, or moxidectin. Feces were collected 2 days before treatment and 14 days after treatment. Additional groups of 7–10 calves were used to test six different two-drug combinations at four of the studied farms. In general terms, fenbendazole was the most effective drug, followed by levamisole, disophenol, and moxidectin. However, parasite resistance to multiple drugs was found in all herds, especially in the genera Cooperia spp., Trichostrongylus spp., and Haemonchus spp.. Some of the two-drug combinations were effective against nematode populations identified as resistant to the same compounds when used as single drugs. The most effective combinations were moxidectin + levamisole, doramectin + fenbendazole, and levamisole + closantel. In this study, parasites resistant to the main commercially available anthelmintics were found in all herds, and some combinations of two active components belonging to different chemical groups were effective against multi-drug resistant gastrointestinal nematodes.

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The effect of anthelmintic resistance on the productivity in feedlot cattle

Cited by 30 publications

References 30 publications

Arthrobotrys cladodes and Pochonia chlamydosporia in the biological control of nematodiosis in extensive bovine production system

Arthrobotrys cladodes and Pochonia chlamydosporia in the biological control of nematodiosis in extensive bovine production system

Association and predatory capacity of fungi Pochonia chlamydosporia and Arthrobotrys cladodes in the biological control of parasitic helminths of bovines

Anthelmintic resistance in gastrointestinal nematodes of beef cattle in the state of Rio Grande do Sul, Brazil

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