The Effect of an Intrauterine Device on Uterine Weight and Water Content and on Genital Tract Glycogen of Cycling, Ovariectomized, Pseudopregnant or Oestrogen-Treated Hamsters

Abstract

The presence of a unilateral IUD resulted in a uterotrophic effect in intact, pseudopregnant and ovariectomized hamsters with or without administration of 10 \g=m\goestrogen. The glycogen content of the uterine horn containing the device was significantly less during pseudopregnancy. While the genital tract responded to oestrogen administration with glycogen synthesis, there was no enhancement of glycogen synthesis with the IUD. No difference in uterine water content was discovered in the presence of the IUD.