The Effect of an Intra-Uterine Plastic Device on the Mast Cell Count in the Rat Uterus

The effect of an intrauterine device on mast cell numbers and distribution in the hamster uterus

“…The stimulatory effect of the IUD on mast cell numbers in the no treatment, peanut oil, estrogen, and all cycling groups agrees with observations of Mathur and Chaudhury [18] made in the rat. The device also causes a redistribution of mast cells and this with the increase in numbers may add further evidence to the theory that the device may be exerting an anti-implantation effect by preventing the release of histamine.…”

“…Not only did the IUD appear to increase the number of mast cells, but there was an apparent redistribution of the mast cells in the various regions Of the uterus. Mathur and Chaudhury [18] have reported that the device increases mast cell numbers in rat uteri but to our knowledge there is no report on the device's effect on mast cell distribution. For this reason, the present study was carefully designed to obtain a statistical evaluation of the effect of an IUD on mast cell numbers and distribution in uteri of castrated, castrated hormone-treated, and cycling hamsters.…”

Distribution and quantitative patterns of mast cells in ovary and uterus of rat

“…Many studies have reported the presence of mast cells in the mammalian uterus (Brandon and Evans 1983, Drudy et al 1990, Jones et al 1980. Besides that, some investigators have also observed an increase in mast cell numbers during progesterone predominance and a decline due to the action of oestrogens (Maraspin and Bo 1971), although others have found no difference throughout the oestrous cycle (Mathur and Chaudhury 1988).…”

“…Using staining of the mast cells with an acidic solution of toluidine blue, some authors have observed an increased quantity of mast cell during progesterone predominance and decreased number due to oestrogens (Maraspin and Bo 1971), while Mathur and Chaudhury (1988) have found no difference throughout the oestrous cycle. The aim of the present study was to establish the pattern of change in mast cell numbers in the uterus and ovary of Wistar Albino rats during the oestrous cycle.…”

Metabolism of [U-14c]glucose in the Rat Uterus in the Presence of an Intra-Uterine Contraceptive Device

“…The presence of an IUD causes endometrial accumulation of glycogen (Parr, 1966), mobilization of mast cells (Mathur & Chaudhury, 1968), increase in total uterine content of histamine (Parr, 1967), transient increase in oxygen consumption (Kar et al, 1965), and an increase in mucopolysaccharide (Cooper & Hawk, 1968) in the uterus. The IUD also causes the uterine fluid to become viscous with increased albumin and globulin concentrations.…”