The effect of an autologous cellular gel-matrix integrated implant system on wound healing

Weinstein‐Oppenheimer, Caroline; Aceituno, Alexis; Brown, Donald I.; Acevedo, Cristián; Ceriani, Ricardo; Fuentes, Miguel A.; Albornoz, Fernando; Henríquez-Roldán, Carlos; Morales, Patricio; Maclean, Claudio; Tapia, Sergio M; Young, Margaret A.

doi:10.1186/1479-5876-8-59

Cited by 36 publications

(28 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Another relevant aspect for the application of hyaluronic acid is the fact of biomaterial being a non-immunogenic substance. An experimental study was conducted to determine the skin tolerance to topical application of hyaluronic acid in full thickness injuries (35% of the body surface area), and it showed the substance was well tolerated and there were no adverse or side effects (35) .…”

Section: Discussionmentioning

confidence: 99%

Hyaluronic acid covers in burn treatment: a systematic review

Dalmedico

Meier

Félix

et al. 2016

Rev. esc. enferm. USP

View full text Add to dashboard Cite

OBJECTIVE To evaluate the effectiveness of hyaluronic acid in the healing of partial thickness burns. METHOD Systematic review of randomized controlled trials on the use of hyaluronic acid for the topical treatment of skin burns, based on recommendations of the Cochrane Handbook for Systematic Reviews of Interventions. RESULTS Two randomized controlled trials that analyzed 143 patients with partial thickness burns and/or deep partial thickness burns were selected. They compared the application of hyaluronic acid 0.2% associated to silver sulfadiazine 1% 5g/cm2 versus silver sulfadiazine 1% 5g/cm2 alone for the outcome of complete healing. CONCLUSION This review emphasizes the need for new well-designed randomized controlled trials to establish the therapeutic relevance of hyaluronic acid with respect to the healing of burns of partial thickness or deep partial thickness.

show abstract

Section: Discussionmentioning

confidence: 99%

Hyaluronic acid covers in burn treatment: a systematic review

Dalmedico

Meier

Félix

et al. 2016

Rev. esc. enferm. USP

View full text Add to dashboard Cite

show abstract

“…Wound healing is one of the most fundamental issues which humanity has faced since its creation. Therefore, various medications have been used to promote wound healing (46,47).…”

Section: Discussionmentioning

confidence: 99%

Wound Healing Effect of an Ointment Made From a Mixture of Brassica oleracea var, Punica granatum, and Plantago major L Extracts in Rats

Bazafkan

Hardani

Zadeh

et al. 2014

Jentashapir J Health Res

View full text Add to dashboard Cite

Background:In Iranian traditional medicine, Punica granatum, cabbage, and plantago have been used to prompt wound healing. The effects of cabbage, Punica granatum, and Plantago in wound healing have been investigated to some extent, but no experimental study has been performed to assess the impact of an ointment containing all these three substances on wound healing. Objectives: The aim of the present study was to evaluate the effect of an ointment prepared from a mixture of cabbage, Punica granatum, and plantago on local wound healing in Wistar rats. Materials and Methods: This experimental study was performed on 21 male Wistar rats. Firstly, a full thickness wound was created on rats flank, near the spine by a bistoury blade and forceps. Then they were randomly divided into three groups of seven rats as the control group, a positive control group (the treatment group with phenytoin), and the third one received a treatment with studied ointment. The wounds were evaluated on days three, six, nine, and 12. Results were compared by SPSS software using ANOVA test. Results: The average percentage of wound healing in different groups on days 3, 6, 9 and 12 were as follows; 21.3%, 37.87%, 67.39% and 77.17% in control group; 24.98%, 34.21%, 70.74% and 88.55% in positive control group; and 32.35%, 61.27%, 94.53%, and 99.91%, in case group. A significant difference was observed between the control and case groups (P < 0.05). Conclusions: Treatment with the studied ointment could promote wound healing.

show abstract

“…Раніше вважалося, що цей несульфатований глікозаміноглікан є одним із важливих компонентів сполучної тканини [6]. Але за останні десятиріччя було показано, що в білій речовині центральної нервової системи гіалуронова кислота локалі-зується навколо мієлінових волокон, а в сірій є однією з основних складових нейрональної сітки, що оточує тіла нейронів.…”

Section: вступunclassified