The Effect of Aluminium on the Planarian Polycelis felina (Daly.)

Kovačević, Goran; Gregorović, Gordana; Jaklinović, Ivica

doi:10.1007/s11270-008-9781-1

Cited by 30 publications

(19 citation statements)

References 33 publications

(12 reference statements)

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“…This can explain the toxic effect on behaviour during the exposure to ammonia: during short pulses, animals take up enough unionized ammonia to cause impairment on the external body layers (epithelial and muscular layer) and/or a decrease of oxygen uptake that can affect the sliding movement of planarians. These effects have been previously observed in aquatic animals (Fromm and Gillette 1968;Kovačevi_ c et al 2009). During the interpulse period, the detoxification mechanism can eliminate ammonia, and the behavioural activity may be recovered until the next pulse.…”

Section: Discussionsupporting

confidence: 77%

Ammonia Toxicity to the Freshwater Planarian Polycelis felina: Contrasting Effects of Continuous Versus Discontinuous Exposures

Alonso

Camargo

2015

Arch Environ Contam Toxicol

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Aquatic animals can be exposed to fluctuating concentrations of toxicants. In fact, for some toxicants (i.e., pesticides, ammonia), discontinuous exposure is more environmentally relevant than constant exposure. Responses of aquatic animals to each type of exposure may be different. However, despite the high ecological relevance of behaviour, there is still scarce information on the effects of discontinuous exposure on behaviour. Our study focused on the assessment of unionized ammonia toxicity on the behaviour of a freshwater planarian under continuous exposure (3 days of exposure and 18 days of recovery) versus discontinuous exposure (3 pulses of 1 day with 6 days of recovery between pulses = total 3 days of exposure and 18 days of recovery). Behaviour was assessed as locomotion activity. Bioassays with continuous and discontinuous exposure were performed with one control and five unionized ammonia concentrations (0.14-0.35 mg N-NH3/L). Unionized ammonia in continuous exposure caused less impact on behaviour than equivalent concentrations provided in a discontinuous exposure. By contrast, continuous exposures caused more impact on survival. The discontinuous exposure may allow detoxification during recovery periods, thus increasing the probability of survival in the next pulse. Under continuous exposure, the mortality threshold could be exceeded, and animals could die in greater proportion during exposure as well as the recovery period. We conclude that behavioural activity was a sensitive endpoint to assess the contrasting effects of continuous versus discontinuous exposure and that the response of planarians to discontinuous exposure is different to its response to continuous exposure.

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Section: Discussionsupporting

confidence: 77%

Ammonia Toxicity to the Freshwater Planarian Polycelis felina: Contrasting Effects of Continuous Versus Discontinuous Exposures

Alonso

Camargo

2015

Arch Environ Contam Toxicol

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“…56: [183][184][185][186][187][188][189][190][191] doi: 10.1387/ijdb.113485mp www.intjdevbiol.com carcinogenicity, etc. (Kapu and Schaeffer, 1991;Guecheva et al, 2003;Pagan et al, 2006;Li, 2008;Kovacevic et al, 2009;Alonso and Camargo, 2011). They are useful in experimental toxicology as they are easy to manipulate in vivo and make it possible to screen for effects at multiple biological levels.…”

Section: Introductionmentioning

confidence: 99%

Physiological and molecular characterisation of cadmium stress in Schmidtea mediterranea

Plusquin

Stevens²,

Belleghem³

et al. 2012

Int. J. Dev. Biol.

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The planarian Schmidtea mediterranea is a well-studied model organism for developmental research, because of its stem cell system. This characteristic also provides a unique opportunity to study stress management and the effect of stress on stem cells. In this study, we characterised the stress signature at different levels of biological organization. The carcinogenic metal cadmium was used as a model chemical stressor. We focused on stem cell activity and its interaction with other known stress parameters. Here, we have found that S. mediterranea is able to cope with high internal levels of cadmium. At endpoints such as size and mobility, cadmium-related stress effects were detected but all of these responses were transient. Correspondingly, cadmium exposure led to an elevated mitotic activity of the neoblasts, at the same time points when the other responses disappeared. At the molecular level, we observed redox-related responses that can be linked with both repair as well as proliferation mechanisms. Together, our results suggest that these animals have a high plasticity. The induction of stem cell activity may underlie this 'restoring' effect, although a carcinogenic outcome after longer exposure times cannot be excluded.

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“…3;2013 deformation and intensive production of mucous ). Production of large quantities of mucous is the result of damage to ectodermal myoepithelial cells, which are capable of secretion activity (Kalafatić, 1995), and this secretion of mucous could represent a mechanism for detoxication (Kovačević, Gregorović, Kalafatić, & Jaklinović, 2009). Mucous layer protects from unfavorable environmental conditions (Burnett, 1973) and increased mucous secretion is noted during treatment of invertebrates with aluminum or other metals (Wilson, Bergman, & Wood, 1994).…”

Section: Resultsmentioning

confidence: 99%

Effects of Quercetin on the Green Hydra (Hydra viridissima Pallas, 1766)

Kovačević¹,

Matulić²

2013

IJB

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Effects of quercetin on the green hydra, Hydra viridissima Pallas, and its endosymbiotic alga were studied under laboratory conditions. Quercetin is the most studied flavonoid known for its ability to act as an antioxidant, but it can also show a pro-oxidative effect. Green hydras were treated with four concentrations of quercetin (0.12 g/L, 0.2 g/L, 0.25 g/L and 0.3 g/L) for three days and compared to the control group of animals. Through the use of light microscopy, morphometry and macroscopic observations the results showed morphological changes in the hydra body as well as behavioral changes: depigmentation, migration, deformation, disordered locomotion, diminished reactions to mechanical stimuli and mortality. Further, different histopathological changes in the hydra body were detected. Different changes were monitored in the endosymbiotic alga: cell viability, division, shape and size of cells and chloroplasts, the level of damage and intensity of green color. Based on our results, the most important conclusion is that quercetin has a possible pro-oxidative effect on the green hydra.

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The Effect of Aluminium on the Planarian Polycelis felina (Daly.)

Cited by 30 publications

References 33 publications

Ammonia Toxicity to the Freshwater Planarian Polycelis felina: Contrasting Effects of Continuous Versus Discontinuous Exposures

Ammonia Toxicity to the Freshwater Planarian Polycelis felina: Contrasting Effects of Continuous Versus Discontinuous Exposures

Physiological and molecular characterisation of cadmium stress in Schmidtea mediterranea

Effects of Quercetin on the Green Hydra (Hydra viridissima Pallas, 1766)

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