The Effect Of Aloe Vera On Healing Process Of Incision Wound

Abstract

Considering the advantages of wound treatment in moist-state, many practitioners always keep the wound in the moist condition. One of the alternatives is by using aloe vera. It has moisturizing effect, anti inflammatory and can stimulate growth factor and fibroblast. In this study, the authors aim to compare the effect of the wound dressing with the dry gauze, moist gauze and aloe vera toward the tensile strength. Thirty Rattus Novergicus were divided into two experimental groups and 1 control group. We performed full thickness skin incision on the back of the rats, and then we sutured and nursed them by using moist gauze and Aloe Vera while the dry gauze group treated as the control. On the 10th day, we decapitated the rats and we took the trace of incisional skin for the tensile strength test. At last, the samples were measured by Zwick universal tensile strength testing machine. This research show that the group treated by dry gauze had tensile strength (35 ± 7 N/cm2) , with moist gauze (41 ± 7 N/cm2), and with Aloe Vera (68 ±17 N/cm2). There was a significant difference between the three groups regarding the tensile strength (p<0.001). Treatment of wound by using Aloe Vera is proven to be more effective than the dry gauze and moist gauze to increase the tensile strength.

Antioxidant and Anti-tyrosinase Activities of <i>Aloe vera</i> Rind and Gel Extracts

“…Originally planted in Indonesia, Aloe vera is used for special skin care treatments. 13 One of the plants that is effective for body and skin health is the Aloe vera plant. This is the background of the authors to examine natural ingredients that are safe and affordable, which can be one of the natural choice ingredients in skin care for skin antioxidants and skin lightening.…”

Efektifitas ekstrak lidah buaya terhadap jumlah sel fibroblast pada proses penyembuhan luka incisi marmut

“…Kandungan acemannans yang terdapat pada ekstrak lidah buaya juga mempunyai efek langsung terhadap fibroblas, acemannans akan meningkatkan proliferasi fibroblas, merangsang fibroblas mengeluarkan Keratinocyte Growth Factor yang akan meningkatkan kecepatan reepitelialisasi dan meningkatkan ketebalan epidermis yang baru saja terbentuk. 7,[11][12][13] Selain berpengaruh terhadap jumlah sel fibroblas dalam proses penyembuhan luka insisi, ekstrak lidah buaya juga berperan dalam penutupan luka insisi. Hasil penelitian menunjukkan bahwa penutupan luka pada luka insisi pertama yang diolesi ekstrak lidah buaya dengan konsentrasi 75% lebih baik dari penutupan luka insisi kedua yang tidak diberi perlakuan.…”

“…Hal ini sejalan dengan penelitian Mahandaru dan Dachlan (2012) yang menyatakan bahwa kekuatan tautan luka insisi yang dirawat dengan kasa lembab yang diberi ekstrak lidah buaya lebih baik dari luka insisi yang dirawat dengan kasa kering. 12,13 Dari hasil penelitian ini maka perlu dilakukan penelitian lebih lanjut dengan menggunakan konsentrasi ekstrak lidah buaya yang lebih tinggi dari 75% dengan parameter yang berbeda.…”