The effect of age on the key parameters in the <scp>C</scp>hicago classification: a study using high‐resolution esophageal manometry in asymptomatic normal individuals

Jung, Kee Wook; Jung, Hwoon Yong; Myung, Seung Jae; Kim, S. O.; Lee, Jeonghyun; Yoon, In Ja; Seo, So Young; Lee, J. H.; Kim, D. H.; Choi, Kee Don; Song, Ho June; Lee, G. H.; Murray, Joseph A.; Romero, Yvonne; Kim, J. H.

doi:10.1111/nmo.12482

Cited by 23 publications

(39 citation statements)

References 40 publications

(115 reference statements)

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“…The absence of difference found in the sitting position did not exclude the possibility of difference in another position. However, the results of comparison between men and women in esophageal motility using HRM found a higher integrated relaxation pressure (IRP) in women than in men in both positions (11) . The median of IRP in women was 9.01 mmHg (95th percentile: 4.26-20.73 mmHg) and in men was 7.02 mmHg (95th percentile: 3.26-14.68 mmHg, P=0.04) in the sitting position, and in the supine position it was 8.06 mmHg (95th percentile: 4.04-18.96 mmHg) in women and 7.40 mmHg (95th percentile: 4.16-14.46 mmHg, P=0.04) in men.…”

Section: Discussionmentioning

confidence: 95%

“…In the sitting position the proportion of abnormal contractions increase (2,10,12) , the distal contraction integral and the amplitude of contractions decrease (4,6,11,12) . It could be, at least in part, the explanation for the absence of difference between men and women.…”

Section: Discussionmentioning

confidence: 97%

“…Previous publications have shown the possibility of differences between men and women in esophageal motility (11)(12)(13)(14) . The results were found using different methods for esophageal motility evaluation, mainly by the water perfusion method.…”

Section: Introductionmentioning

confidence: 97%

“…The investigations about gender influence on esophageal motility have described that: integrated relaxation pressure of the lower esophageal sphincter (LES) is higher in women than in men (11) ; contractions in proximal esophagus have a higher area under the curve in women (7) ; women have an increase in contraction duration in distal esophagus (8) ; women have a higher LES pressure, higher distal amplitude, longer distal contraction duration and slower distal velocity of peristaltic contraction (14) . Gender does not influence whether esophageal motility is normal, spastic or with a non-specific motor disorder (1) .…”

Section: Introductionmentioning

confidence: 99%

“…A previous evaluation of the effect of gender in esophageal motility with the method of HRM, with the main focus on distal Esophageal motility in men and women evaluated by high-resolution manometry Tarciana Vieira COSTA 1 and Roberto Oliveira DANTAS 2 esophagus, described the difference of high integrated relaxation pressure (IRP) in women compared with men as unique (11) , being measured in both supine and sitting positions and with a 5 mL saline bolus. In the present investigation our objective was to evaluate, by HRM in the sitting position and swallows of a 5 mL saline bolus, the proximal and distal esophageal motility in men and women, with the hypothesis that the esophageal contraction in women has some differences when compared with the esophageal contraction of men.…”

Section: Introductionmentioning

confidence: 99%

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Esophageal Motility in Men and Women Evaluated by High-Resolution Manometry

Costa

Dantas

2017

Arq. Gastroenterol.

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-Background -Esophageal motility has been described in the literature as having differences between men and women. Most of these investigations use the water perfusion method for esophageal manometry. In this investigation the esophageal motility of men and women was compared with high-resolution manometry of the esophagus. Objective -To compare the esophageal motility of men and women with the high-resolution manometry method for esophageal manometry, performed in the sitting position. The hypothesis was that men and women have differences in esophageal motility. Methods -High-resolution manometry was performed in normal volunteers, 10 men [mean age: 37.5 (8.1) years] and 12 women [mean age: 38.7 (7.5) years], in the sitting position and with 10 swallows of a 5 mL bolus of saline, with an interval of at least 30 seconds between consecutive swallows. We evaluated the integrated relaxation pressure of the lower esophageal sphincter, contraction front velocity, distal contraction integral, distal latency, proximal contraction extension, proximal contraction duration >30 mmHg, proximal contraction duration, proximal contraction integral and maximal upper esophageal sphincter pressure. Results -There was no significant difference between men and women in the variables measured. Conclusion -There was no difference in esophageal motility of men and women evaluated by the high resolution manometry method, in the sitting position with swallows of a liquid bolus. HEADINGS -Gastrointestinal motility. Manometry, methods. Sex factors.

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Section: Discussionmentioning

confidence: 95%