1987
DOI: 10.1016/0010-7824(87)90099-0
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The effect of acetylsalicylic acid on menstrual blood loss in women with IUDs

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Cited by 9 publications
(17 citation statements)
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“…Data regarding the overall safety of tranexamic acid are limited; an FDA warning states that tranexamic acid is contraindicated in women with active thromboembolic disease or with a history or intrinsic risk for thrombosis or thromboembolism (136,137). Treatment with aspirin demonstrated no statistically significant change in mean blood loss among women whose pretreatment menstrual blood loss was >80 ml or 60-80 mL; treatment resulted in a significant increase among women whose pretreatment menstrual blood loss was <60 mL (138). One study examined the use of a synthetic form of vasopressin, intranasal desmopressin (300 µg/day), for the first 5 days of menses for three treatment cycles and found a significant reduction in mean blood loss compared with baseline (130) (Level of evidence: I to II-3, poor to fair, direct).…”
Section: Bleeding Irregularities With Cu-iud Usementioning
confidence: 84%
“…Data regarding the overall safety of tranexamic acid are limited; an FDA warning states that tranexamic acid is contraindicated in women with active thromboembolic disease or with a history or intrinsic risk for thrombosis or thromboembolism (136,137). Treatment with aspirin demonstrated no statistically significant change in mean blood loss among women whose pretreatment menstrual blood loss was >80 ml or 60-80 mL; treatment resulted in a significant increase among women whose pretreatment menstrual blood loss was <60 mL (138). One study examined the use of a synthetic form of vasopressin, intranasal desmopressin (300 µg/day), for the first 5 days of menses for three treatment cycles and found a significant reduction in mean blood loss compared with baseline (130) (Level of evidence: I to II-3, poor to fair, direct).…”
Section: Bleeding Irregularities With Cu-iud Usementioning
confidence: 84%
“… 18 Aspirin has not been shown to be effective in decreasing menstrual blood loss in Cu-IUD users. 1 , 19 Limited evidence exists regarding use of intranasal desmopressin to decrease mean blood loss. 1 , 20 …”
Section: Copper-intrauterine Devicementioning
confidence: 99%
“…In total, 742 records were identified by our database search, of which 607 potentially relevant unique articles were screened based on titles and abstracts ( Figure 1 ) [ 21 ]. Full-text screening was subsequently performed on 75 records, of which 13 studies were finally included [ [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] ]. Excluded studies and reasons for exclusion are listed in the Supplementary material (Item 16b of PRISMA 2020 checklist).…”
Section: Resultsmentioning
confidence: 99%