The Effect of a Series of Repetitive Transcranial Magnetic Stimulations of the Motor Cortex on Central Pain After Spinal Cord Injury

Defrin, Ruth; Grunhaus, Leon; Zamir, Doron; Zeilig, Gabi

doi:10.1016/j.apmr.2007.07.025

Cited by 129 publications

(112 citation statements)

References 49 publications

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“…Three RCTs in SCI-related NP compared the effect of transcranial magnetic stimulation with sham therapy. [54][55][56] Two of these trials found no significant difference in reduction in pain intensity. 54,55 The evidence quality of the third trial, which found a significant improvement in pain intensity after treatment, was downgraded because of wide confidence intervals.…”

Section: ) Treatments With Low-quality Evidence Of Positive Effectmentioning

confidence: 99%

“…[54][55][56] Two of these trials found no significant difference in reduction in pain intensity. 54,55 The evidence quality of the third trial, which found a significant improvement in pain intensity after treatment, was downgraded because of wide confidence intervals. 56 2) Treatments with evidence of positive effect in populations other than SCI The SC evaluated several therapies with evidence of pain reduction in non-SCI populations, including cannabinoids, duloxetine and intrathecal clonidine.…”

Section: ) Treatments With Low-quality Evidence Of Positive Effectmentioning

confidence: 99%

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The CanPain SCI Clinical Practice Guidelines for Rehabilitation Management of Neuropathic Pain after Spinal Cord: Recommendations for treatment

et al. 2016

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Study design: Clinical practice guidelines. Objectives: To develop the first Canadian clinical practice guidelines for treatment of neuropathic pain in people with spinal cord injury (SCI). Setting: The guidelines are relevant for inpatient and outpatient SCI rehabilitation settings in Canada. Methods: The CanPainSCI Working Group reviewed the evidence for different treatment options and achieved consensus. The Working Group then developed clinical considerations for each recommendation. Recommendations for research are also included. Results: Twelve recommendations were developed for the management of neuropathic pain after SCI. The recommendations address both pharmacologic and nonpharmacologic treatment modalities. Conclusions: An expert Working Group developed recommendations for the treatment of neuropathic pain after SCI that should be used to inform practice.

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Section: ) Treatments With Low-quality Evidence Of Positive Effectmentioning

confidence: 99%

Section: ) Treatments With Low-quality Evidence Of Positive Effectmentioning

confidence: 99%

The CanPain SCI Clinical Practice Guidelines for Rehabilitation Management of Neuropathic Pain after Spinal Cord: Recommendations for treatment

et al. 2016

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“…4 In particular, repetitive transcranial magnetic stimulation (rTMS) approaches have been implemented with promising results either in human or experimental models. 5 Herein, we describe the application of a combined neurorobotic-non-invasive neuromodulation rehabilitative protocol in a case of post-traumatic incomplete SCI in the chronic phase.…”

Section: Introductionmentioning

confidence: 99%

Usefulness of robotic gait training plus neuromodulation in chronic spinal cord injury: a case report

Calabrò

Naro

Leo

et al. 2016

The Journal of Spinal Cord Medicine

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Context: Spinal cord injury (SCI) affects more than 2.5 million people worldwide, often leading to severe disability. Thus, a proper management of individuals with SCI is required either in the acute or in the postacute rehabilitative phase. Findings: A 31-year-old man, affected by chronic SCI, underwent two different intensive rehabilitation treatments, including either LokomatPro or a paired LokomatPro-rTMS training. We evaluated the clinical, kinetic, and electrophysiological parameters before and after each training session. In particular, the intensive robotic training was articulated in a total of 40 one-hour training sessions (i.e. 5 times a week for 8 weeks), whereas the rTMS sessions were delivered 3 days per week for 3 consecutive weeks, just before the LokomatPro session. Only at the end of the experimental treatment, we observed an important improvement in nearly all parameters we investigated. Clinical relevance: The combined LokomatPro-rTMS rehabilitation may be a valuable approach in improving the motor function in patients affected by SCI, even in the chronic phase.

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“…Self-report pain assessment tools Pain assessment tools such as numerical and verbal rating scales are simple to administer and attempt to make the pain experience 'measureable' by categorizing and quantifying aspects of the experience. These tools have been used in research settings to measure changes in intra-individual pain across time (Defrin, Grunhaus, Zamir, & Zeilig, 2007;McCaffrey & Freeman, 2003), and distinguish between different types of pain (Crawford, 2009;Dubuisson & Melzack, 1976). However, it is not clear that these tools necessarily provide more detailed or useful information than would be obtained from verbal self-report.…”

Section: Alternative Methods Of Obtaining Information About Painmentioning

confidence: 99%

Externalizing the Private Experience of Pain: A Role for Co-Speech Gestures in Pain Communication?

Rowbotham

Lloyd

Holler

et al. 2014

Health Communication

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The Effect of a Series of Repetitive Transcranial Magnetic Stimulations of the Motor Cortex on Central Pain After Spinal Cord Injury

Cited by 129 publications

References 49 publications

The CanPain SCI Clinical Practice Guidelines for Rehabilitation Management of Neuropathic Pain after Spinal Cord: Recommendations for treatment

The CanPain SCI Clinical Practice Guidelines for Rehabilitation Management of Neuropathic Pain after Spinal Cord: Recommendations for treatment

Usefulness of robotic gait training plus neuromodulation in chronic spinal cord injury: a case report

Externalizing the Private Experience of Pain: A Role for Co-Speech Gestures in Pain Communication?

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