The Effect of a Mandibular Advancement Device on Apneas and Sleep in Patients With Obstructive Sleep Apnea

Marklund, Marie; Franklin, Karl A.; Sahlin, Carin; Lundgren, R

doi:10.1378/chest.113.3.707

Cited by 131 publications

(106 citation statements)

References 16 publications

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“…These results of this study are in agreement with many previous studies [3,4,[14][15][16][17][18][19]24,25]. Mild and moderate OSAS responded effectively to MAD treatment.…”

Section: Moderate Ahi Groupsupporting

confidence: 93%

“…In our own previously published study we showed that BMAS of the jaws improved OSAS airway parameters [12] and relieved the symptoms of OSAS [13]. A conservative non-surgical technique involving a tooth-borne appliance to advance the mandible without surgery also known as the MAD has already been introduced in the late 1990`s [3]. MAD has been shown, to provide satisfactory treatment of mild to moderate OSAS [4,14].…”

Section: Introductionmentioning

confidence: 96%

“…Conservative treatment includes weight loss and the regular use of Continuous Positive Airway Pressure (C-PAP) equipment and a variety of devices that attempt to keep tissues in the anterior part of the upper airway forward. These devices include mandibular advancement devices (MAD), and tongue holding devices [3,4]. C-PAP treatment has been regarded as the "gold standard" in the treatment of OSAS [4].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The Influence of a Mandibular Advancement Plate on Polysomnography in Different Grades of Obstructive Sleep Apnea

Raunio¹,

Mattila²,

Huuskonen³

et al. 2015

JOMR

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Objectives: The purpose of this study was to investigate the effect of a mandibular advancement device on different grades of obstructive sleep apnea using a relatively simple test for the apnea-hypopnea index to determine if a mandibular device will be effective. Material and Methods: A total of 68 patients with obstructive sleep apnea syndrome (OSAS) including, 31 with mild, 23 with moderate and 14 with severe OSAS were treated with a mandibular advancement device (MAD) and monitored with polysomnography. Results: 25 of the 31 mild, 15 of the 23 moderate and 2 of the 14 severe OSAS patients were cured of their OSAS if a post treatment apnea-hypopnea index of less than 5 is regarded as cured. The odds ratios for success with MAD therapy are 3 for women over men, 14.9 for mild obstructive sleep apnea, 5.42 for moderate obstructive sleep apnea if severe obstructive sleep apnea is assigned an odds ratio of 1. Conclusions: The use of the apnea-hypopnea index alone is useful in mild and moderate disease to predict the effectiveness of mandibular advancement device. Treatment with a mandibular advancement device is very effective in treating mild and moderate obstructive sleep apnea. Conservative treatment with a mandibular advancement device can be successful in less severe grades of sleep apnea and may be an alternative for non-surgical patients with severe obstructive sleep apnea intolerant of Continuous Positive Airway Pressure management.

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“…These results of this study are in agreement with many previous studies [3,4,[14][15][16][17][18][19]24,25]. Mild and moderate OSAS responded effectively to MAD treatment.…”

Section: Moderate Ahi Groupsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Influence of a Mandibular Advancement Plate on Polysomnography in Different Grades of Obstructive Sleep Apnea

Raunio¹,

Mattila²,

Huuskonen³

et al. 2015

JOMR

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“…The influence of AHI on change in overjet may be explained by the fact that patients with more severe OSA could be more likely to have their mandibles advanced a greater amount to see a relief in symptoms compared to patients with a milder degree of the disease. 29 It has been previously shown that the relationship between the force applied to the arches and amount of mandibular advancement is almost linear, with the force increasing with increasing mandibular advancement. 24 In the present study, patients with a greater amount of initial overjet tended to see larger total reductions to both overjet and overbite.…”

Section: Discussionmentioning

confidence: 98%

Obstructive Sleep Apnea and Mandibular Advancement Splints: Occlusal Effects and Progression of Changes Associated with a Decade of Treatment

Pliska

Nam

Chen

et al. 2014

Journal of Clinical Sleep Medicine

106

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However, some of these studies are limited by a relatively short observation period, considering that MAS treatment may continue indefi nitely through a patient's lifetime.Previous studies examining effects over at least a 5-year treatment period have shown signifi cant decreases in overbite (OB)-the vertical overlap of the anterior teeth, and overjet (OJ)-the horizontal overlap of the anterior teeth, ranging from 0.6-1.91 mm and 0.6-1.24 mm, respectively, after long-term appliance use. [16][17][18] These studies also report various BRIEF SUMMARYCurrent Knowledge/Study Rationale: Mandibular advancement splints are an effective treatment option for OSA patients, with changes to the dental occlusion as a common side effect. Due to the indefi nite nature of OSA treatment a clear understanding of the magnitude and progression of long-term occlusal changes is needed. Study Impact: With the longest observation period yet to be reported, the results from this study confi rm that long-term MAS treatment leads to signifi cant changes in occlusion for the majority of patients. These dental changes were found to be progressive in nature, and continue with ongoing MAS use.

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“…Several studies concerning the effectiveness of (MAA) therapy in treating mild and moderate obstructive sleep apnea are available, however, little is known from the relevant literatures about their effectiveness and compliance with respect to severe OSAS patients [10,11].…”

Section: Introductionmentioning

confidence: 99%

Can Oral Appliances be an Alternative Treatment for Severe Obstructive Sleep Apnea Syndrome Patients?

ElWaseef¹

2014

J Pulm Respir Med

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Background: Obstructive Sleep Apnea Syndrome (OSAS) is recognized as a serious health problem that impairs quality of life. Although, optimal treatment of OSAS with continuous positive airway pressure (CPAP) reduce the number of respiratory events during sleep, and thus improve quality of life, a large number of patients do not tolerate CPAP. In the last decade, there has been an explosion of interest in the using of oral appliances to treat OSAS; however, in severe OSAS there is only scanty evidence available indicating that dental appliances are effective.

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The Effect of a Mandibular Advancement Device on Apneas and Sleep in Patients With Obstructive Sleep Apnea

Cited by 131 publications

References 16 publications

The Influence of a Mandibular Advancement Plate on Polysomnography in Different Grades of Obstructive Sleep Apnea

The Influence of a Mandibular Advancement Plate on Polysomnography in Different Grades of Obstructive Sleep Apnea

Obstructive Sleep Apnea and Mandibular Advancement Splints: Occlusal Effects and Progression of Changes Associated with a Decade of Treatment

Can Oral Appliances be an Alternative Treatment for Severe Obstructive Sleep Apnea Syndrome Patients?

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