The Effect of a Light‐Cured Periodontal Dressing Material on HeLa Cells and Fibroblasts In Vitro

Gilbert, Antoine; Lloyd, C.H.; Scrimgeour, S. N.

doi:10.1902/jop.1994.65.4.324

Cited by 12 publications

(8 citation statements)

References 3 publications

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“…In our study Barricaid dressing showed the lowest inhibitory effect on cell proliferation (growth rate was reduced to 83.3 ± 9% of control after 48 h) and cell survival (SF = 0.41 ± 0.09) with fully cured material. Gilbert et al (1994) and Alpar et al (1999) also found no cytotoxic alterations on fibroblasts and HeLa cells with fully cured dressing. In contrast, direct contact of uncured material caused growth inhibition and cell death.…”

Section: Discussionmentioning

confidence: 86%

“…Mouse fibroblasts (L 929, 3T3 cells), Hela cells, human epithelial cells, human gingival fibroblasts and leukocytes have been used (Hildebrand and De Rensis, 1974;Rivera-Hidalgo et al, 1977;Haugen and Hensten-Pettersen, 1978;Gilbert et al, 1994;Alpar et al, 1999). Soluble material leached from some formed dressings has been found toxic to cells in culture (Hildebrand and De Rensis, 1974;Rivera-Hidalgo et al, 1977) and dilution of soluble extracts from periodontal dressings decreased this toxic effect (Eber et al, 1989;Alpar et al, 1999).…”

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confidence: 99%

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Effects of periodontal dressings on fibroblasts and gingival wound healing in dogs

Petelin

Pavlica

Batista

et al. 2004

Acta Veterinaria Hungarica

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In the present study the effects of different commercially available periodontal dressings (Peripac, Barricaid, Fittydent, Reso-Pack and Myzotect-tincture) on fibroblast (V-79-379A) proliferation and survival were tested in vitro. Barricaid, Fittydent and Reso-Pack periodontal dressings have only small inhibitory effects on cell proliferation (83.3 ± 9%, 71.6 ± 8.7% and 87.3 ± 4.5% of control after 48 h, respectively) in comparison with the great inhibitory effect of Myzotecttincture (2.9 ± 0.1%) and Peripac (33.7 ± 11.4%) (p < 0.001). Barricaid was the only dressing where 41% of cells survived after exposure, while the other four dressings killed all the cells in 6 days. In addition, the healing of artificially created gingival wounds covered by Barricaid and Reso-Pack was followed for 7 days in 12 Beagle dogs. Histological evaluation of gingival tissue demonstrated that wounds covered by Reso-Pack showed the best epithelisation and vascularity and the least inflammatory reaction in first 4 days. Later the observed parameters were similar with those of wounds covered by Barricaid or without pack. The present results indicate that Peripac periodontal dressing and Myzotect-tincture showed the highest cytotoxicity to fibroblasts in vitro. From the histological observations in Beagle dogs Reso-Pack has been found to be the most suitable dressing, followed by Barricaid.

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Section: Discussionmentioning

confidence: 86%

mentioning

confidence: 99%

Effects of periodontal dressings on fibroblasts and gingival wound healing in dogs

Petelin

Pavlica

Batista

et al. 2004

Acta Veterinaria Hungarica

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“…(1994). [11] Hence, the present study was planned to compare the biocompatibility and patient acceptance of this new pack with age-old rosin-based “Coe-pak.”…”

Section: Discussionmentioning

confidence: 99%

Light-cured resin "Barricaid" - An aesthetic and biocompatible dressing: A step ahead

Madan

Bharti

Chaubey

et al. 2013

J Indian Soc Periodontol

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Background:Periodontal dressings have been used for several years as a protection over injured tissue to shield the area from further insult. Several dressings are commercially available. A recently introduced light-cured resin, claimed to be more biocompatible and esthetic, needs critical evaluation.Aim:To compare this dressing with most widely used non-eugenol pack in the perspective of esthetics, acceptance, and healing following periodontal flap surgery.Materials and Methods:Twenty patients suffering from generalized chronic periodontitis, requiring periodontal flap surgery on contralateral sides of the arch, were selected and divided randomly into Group I (control) and Group II (test). In Group I, a non-eugenol dressing and in Group II light-cured dressing were applied after flap surgery. Pain and discomfort scores were recorded on day 1, 2, and 3 while plaque scores, gingival index, and bleeding index were recorded on day 7. Patient's subjective evaluation and preference for the dressing material were recorded. The data was collected and statistically analyzed.Results:Group II showed better results than Group I when plaque scores, bleeding scores, modified gingival index scores, and pain and discomfort scores were compared though the differences were not statistically significant. Subjects found no unpleasant taste/smell and perceived the light-cured dressing to be better. A significantly higher number of patients preferred light-cured resin as a post-surgical dressing over Coe-pak.Conclusion:The light-cured dressing showed better patient acceptability and proves to be a better alternative to Coe-pak as a dressing material.

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“…This slight more discomfort at Barricaid treated sites might be contributed by uncured residual monomer underlying the cured surface at deeper strata. This was previously justified by the study of Gilbert AD 18 showing the effect of light cured Periodontal dressing material on gingival cells. This problem can be countersink by raising the curing time upto 40 second especially in interproximal area where it was thickest after placement.…”

Section: Discussionmentioning

confidence: 92%

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2017

IJPSR

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Periodontal dressings were widely used after flap surgery to protect the surgical site since long. This study compared polyether urethane dimethacrylate resin based Barricaid dressing and non-eugenol based periodontal dressings in the perspective of pain, esthetics and patient acceptance using a randomized split-mouth study design. Fifteen patients coming to the Department of Periodontics at ITS Dental College and diagnosed as a case of generalized chronic periodontitis were selected. Total 30sites (2 sites in each patient) requiring the flap surgery were selected and contralateral sites in each patient were randomly allocated into two groups. At baseline plaque index, Modified gingival index were recorded. In group-1 non-eugenol dressing and in group-II light cured periodontal dressing were applied to secure the surgical sites after flap surgery. At day1,2 and 3 pain and discomort was assessed using Numeric Pain Rating Scale.(NPRS) After 7 days patients were recalled for removal of dressing, recording the indices and asked to fill a questionarrie regarding the patient acceptability. Collected data were subjected to statistical analysis and non-significant difference was found in mean NPRS between both groups. After 7 days there was statistically significant better taste, smell and appearance for Barricaid group patients as compared to Coe-pack group. In summation, Barricaid is more preferred dressing over Coe-pack.

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The Effect of a Light‐Cured Periodontal Dressing Material on HeLa Cells and Fibroblasts In Vitro

Cited by 12 publications

References 3 publications

Effects of periodontal dressings on fibroblasts and gingival wound healing in dogs

Effects of periodontal dressings on fibroblasts and gingival wound healing in dogs

Light-cured resin "Barricaid" - An aesthetic and biocompatible dressing: A step ahead

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