The effect of 904 nm low level laser on condylar growth in rats

Seifi, Massoud; Maghzi, Arezoo; Gutknecht, Norbert; Mir, Maziar; Asnaashari, Mohammad

doi:10.1007/s10103-009-0651-x

Cited by 22 publications

(23 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recently, low-level laser was used to enhance bone healing after fracture [16,17], after mandibular distraction osteogenesis,[18,19] and also for condylar growth stimulation [20]. The results suggest that Low level laser therapy(LLLT) had a positive effect on the percentage of newly formed bone.…”

Section: Introductionmentioning

confidence: 99%

The effect of low level laser on condylar growth during mandibular advancement in rabbits

et al. 2012

View full text Add to dashboard Cite

IntroductionIt has been shown that Low Level Laser (LLL) has a positive effect on bone formation. The aim of this study was to evaluate the effect of low level laser on condylar growth during mandibular advancement in rabbits.Materials and methodsContinuous forward mandibular advancement was performed in fourteen male Albino rabbits with the mean age of 8 weeks and the mean weight of 1.5 ± 0.5 kg, with acrylic inclined planes. The rabbits were randomly assigned into two groups after 4 weeks. LLL (KLO3: wave length 630 nm) was irradiated at 3 points around the TMJ, through the skin in the first group. The exposure was performed for 3 minutes at each point (a total of 9 minutes) once a day for 3 weeks. The control group was not exposed to any irradiation. The rabbits in both groups were sacrificed after two months and the histological evaluation of TMJ was performed to compare fibrous tissue, cartilage, and new bone formation in condylar region in both groups. Disc displacement was also detected in both groups. Student's t-test, Exact Fisher and Chi square tests were used for the statistical analysis.ResultsThe formation of fibrous tissue was significantly lower, while bone formation was significantly greater in lased group as compared with control group. The thickness of cartilage did not differ significantly between two groups.ConclusionIrradiation of LLL (KLO3) during mandibular advancement in rabbits, increases bone formation in condylar region, while neither increase in the cartilage thickness nor fibrous tissues was observed.

show abstract

Section: Introductionmentioning

confidence: 99%

The effect of low level laser on condylar growth during mandibular advancement in rabbits

et al. 2012

View full text Add to dashboard Cite

show abstract

“…Unlike our study, Seifi et al [17] applied LLLT with a wavelength of 904 nm, in the condyles of 42-day-old rats with 0.24 J/cm 2 , for prolonged periods. They observed a significant increase in the animals' mandible length.…”

Section: Discussionmentioning

confidence: 70%

The Effects of Low-Level Laser Therapy, 670 nm, on Epiphyseal Growth in Rats

Andrade

Meireles

Artifon

et al. 2012

The Scientific World Journal

View full text Add to dashboard Cite

The longitudinal growth of long bones is attributed to epiphyseal growth. However, the effects of low-level laser therapy (LLLT) in such structures has still not been studied extensively in the literature. Therefore, the aim of this study was to evaluate the use of LLLT, 670 nm, at three different doses on the epiphyseal growth of the right tibia of rats. Twenty-one Wistar rats, aged four weeks, were subjected to the application of LLLT, with dosage according to the group (G4: were submitted to the application of 4 J/cm2; G8: were submitted to the application of 8 J/cm2; G16: were submitted to the application of 16 J/cm2). After completion of protocol they were kept until they were 14 weeks of age and then submitted to a radiological examination (evaluation of limb length) and euthanised. The histological analysis of the growth plates (total thickness and hypertrophic and proliferative zones) was then performed. Comparisons were made with the untreated left tibia. No differences were observed in any of the reviews (radiological and histological), when comparing the right sides (treated) to the left (untreated). It was concluded that the treatment with LLLT within the parameters used caused changes neither in areas of the epiphyseal cartilage nor in the final length of limbs.

show abstract

“…In another study, irradiation of the rat mandible growth center (Α=904 nm, 2000 Hz, pulse length 200 ns and output power 4 mW) on days 0, 2, 4, 6, 8 and 10, with the protocol repeated after a 50-day interval, produced higher growth than that observed in controls 15 . In both studies the type of bone irradiated, and the total dose, points and intervals of irradiation, among other factors, may have contributed to the differences in results.…”

Section: Discussionmentioning

confidence: 93%

Low-level laser on femoral growth plate in rats

Oliveira¹,

Rahal

Pereira

et al. 2012

Acta Cir. Bras.

View full text Add to dashboard Cite

PURPOSE:To determine the influence of low-level laser therapy on femoral growth plate in rats. METHODS:Thirty male Wistar rats aged 40 days were divided into two groups, G1 and G2. In G1 the area of the distal growth plate of the right femur was irradiated at one point using GaAlAs laser 830 nm wavelength, output power of 40 mW, at an energy density of 10 J/cm 2 . The irradiation was performed daily for a maximum of 21 days. The same procedure was done in G2, but the probe was turned off. Five animals in each group were euthanized on days 7, 14 and 21 and submitted to histomorphometric analysis. RESULTS:In both groups the growth plate was radiographically visible at all moments from both craniocaudal and mediolateral views.On the 21st day percentage of femoral longitudinal length was higher in G2 than G1 compared to basal value while hypertrophic zone chondrocyte numbers were higher in G1 than G2. Calcified cartilage zone was greater in G1 than in G2 at all evaluation moments.Angiogenesis was higher in G1 than in G2 at 14th and 21st days. CONCLUSION:The low-level laser therapy negatively influenced the distal femoral growth plate.Key words: Lasers. Bone Development. Chondrocytes. Laser Therapy, Low-Level. Rats. RESUMO OBJETIVO:Determinar a influência do Laser Terapêutico de Baixa Potência sobre a placa de crescimento de ratos. MÉTODOS:Trinta ratos Wistar machos com 40 dias de idade foram divididos em dois grupos, G1 e G2. O grupo G1 foi submetido à irradiação com laser GaAlAs 830 nm, potência de saída de 40 mW, e densidade de energia de 10 J/cm2. A irradiação foi aplicada diariamente por um período máximo de 21 dias. O mesmo procedimento foi realizado no grupo G2, com a probe desativada. Cinco animais em cada grupo foram sacrificados nos dias 7, 14 e 21 e submetidas à análise histomorfométrica. RESULTADOS:Em ambos os grupos, o disco fisário esteve radiograficamente visível em todos os momentos nas incidências craniocaudal e médio-lateral. No 21º dia a porcentagem de comprimento longitudinal do fêmur foi maior em G1 que em G2 em relação ao valor basal, e o número de condrócitos da zona hipertrófica foi maior em G1 que em G2. A zona de cartilagem calcificada estava maior em G1 em relação a G2 em todos os momentos de avaliação. A angiogênese foi maior em G1 que em G2 nos 14º e 21º dias. CONCLUSÃO:A terapia com laser terapêutico de baixa potência influenciou negativamente o disco fisário distal do fêmur de ratos.Descritores: Lasers. Desenvolvimento Ósseo. Condrócitos. Terapia a Laser de Baixa Intensidade. Ratos.Oliveira SP et al.

show abstract

The effect of 904 nm low level laser on condylar growth in rats

Cited by 22 publications

References 21 publications

The effect of low level laser on condylar growth during mandibular advancement in rabbits

The effect of low level laser on condylar growth during mandibular advancement in rabbits

The Effects of Low-Level Laser Therapy, 670 nm, on Epiphyseal Growth in Rats

Low-level laser on femoral growth plate in rats

Contact Info

Product

Resources

About